Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060691279> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2060691279 endingPage "159" @default.
- W2060691279 startingPage "151" @default.
- W2060691279 abstract "C3H/HeJ-gld/gld(C3H/gld) mice have been shown to develop massive lymphadenopathy with autoimmunity. In this study, we tested whether C3H/gld-IgG supports the growth of the IL-3-dependent cell line, FDC-P2/185-4. Serum IgG from C3H/gld mice stimulated FDC-P2/ 185-4 cells to proliferate. On the other hand, IgG from C3H/HeJ-+/+ did not show such activity. This activity increased with age in both sexes of C3H/gld mice. It was suggested that a monomeric IgG component was responsible for the proliferative activity of C3H/gld mouse sera. The cell-induced growth required fcγ receptors on FDC-P2/185-4 cells. FDC-P2/185-4 cells stimulated with C3H/gld-IgG, secreted IL-3, and grew by themselves, indicating an autocrine mechanism. Thus, cytokines produced by serum IgG may play an important role in the development of disease in mice bearing the autosomal recessive mutation gld." @default.
- W2060691279 created "2016-06-24" @default.
- W2060691279 creator A5006295807 @default.
- W2060691279 creator A5011544616 @default.
- W2060691279 creator A5037581848 @default.
- W2060691279 creator A5063350161 @default.
- W2060691279 creator A5063789588 @default.
- W2060691279 creator A5075627743 @default.
- W2060691279 date "1990-01-01" @default.
- W2060691279 modified "2023-09-25" @default.
- W2060691279 title "Serum IgG from an autoimmune prone mouse C3H/HeJ-gld/gld supports the interleukin-3-dependent cell line through an autocrine mechanism" @default.
- W2060691279 cites W1495263084 @default.
- W2060691279 cites W1512217363 @default.
- W2060691279 cites W1513352958 @default.
- W2060691279 cites W1534110338 @default.
- W2060691279 cites W1537020111 @default.
- W2060691279 cites W1569831030 @default.
- W2060691279 cites W1675574531 @default.
- W2060691279 cites W1679112942 @default.
- W2060691279 cites W1751411118 @default.
- W2060691279 cites W1968981783 @default.
- W2060691279 cites W1978947335 @default.
- W2060691279 cites W1982920370 @default.
- W2060691279 cites W2026856641 @default.
- W2060691279 cites W2090404200 @default.
- W2060691279 cites W2114918609 @default.
- W2060691279 cites W2126715968 @default.
- W2060691279 cites W2142269895 @default.
- W2060691279 cites W2142360671 @default.
- W2060691279 cites W2146561639 @default.
- W2060691279 cites W2165835604 @default.
- W2060691279 cites W2227157639 @default.
- W2060691279 doi "https://doi.org/10.1016/0008-8749(90)90070-8" @default.
- W2060691279 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2293897" @default.
- W2060691279 hasPublicationYear "1990" @default.
- W2060691279 type Work @default.
- W2060691279 sameAs 2060691279 @default.
- W2060691279 citedByCount "7" @default.
- W2060691279 crossrefType "journal-article" @default.
- W2060691279 hasAuthorship W2060691279A5006295807 @default.
- W2060691279 hasAuthorship W2060691279A5011544616 @default.
- W2060691279 hasAuthorship W2060691279A5037581848 @default.
- W2060691279 hasAuthorship W2060691279A5063350161 @default.
- W2060691279 hasAuthorship W2060691279A5063789588 @default.
- W2060691279 hasAuthorship W2060691279A5075627743 @default.
- W2060691279 hasConcept C128240485 @default.
- W2060691279 hasConcept C159654299 @default.
- W2060691279 hasConcept C170493617 @default.
- W2060691279 hasConcept C203014093 @default.
- W2060691279 hasConcept C2777371288 @default.
- W2060691279 hasConcept C2778690821 @default.
- W2060691279 hasConcept C2780130043 @default.
- W2060691279 hasConcept C54355233 @default.
- W2060691279 hasConcept C86803240 @default.
- W2060691279 hasConceptScore W2060691279C128240485 @default.
- W2060691279 hasConceptScore W2060691279C159654299 @default.
- W2060691279 hasConceptScore W2060691279C170493617 @default.
- W2060691279 hasConceptScore W2060691279C203014093 @default.
- W2060691279 hasConceptScore W2060691279C2777371288 @default.
- W2060691279 hasConceptScore W2060691279C2778690821 @default.
- W2060691279 hasConceptScore W2060691279C2780130043 @default.
- W2060691279 hasConceptScore W2060691279C54355233 @default.
- W2060691279 hasConceptScore W2060691279C86803240 @default.
- W2060691279 hasIssue "1" @default.
- W2060691279 hasLocation W20606912791 @default.
- W2060691279 hasLocation W20606912792 @default.
- W2060691279 hasOpenAccess W2060691279 @default.
- W2060691279 hasPrimaryLocation W20606912791 @default.
- W2060691279 hasRelatedWork W2009135789 @default.
- W2060691279 hasRelatedWork W2009685269 @default.
- W2060691279 hasRelatedWork W2011666100 @default.
- W2060691279 hasRelatedWork W2017946667 @default.
- W2060691279 hasRelatedWork W2026232544 @default.
- W2060691279 hasRelatedWork W2119122291 @default.
- W2060691279 hasRelatedWork W2142624029 @default.
- W2060691279 hasRelatedWork W2395961148 @default.
- W2060691279 hasRelatedWork W3101274966 @default.
- W2060691279 hasRelatedWork W3111477311 @default.
- W2060691279 hasVolume "125" @default.
- W2060691279 isParatext "false" @default.
- W2060691279 isRetracted "false" @default.
- W2060691279 magId "2060691279" @default.
- W2060691279 workType "article" @default.