FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060694966> ?p ?o ?g. }

• W2060694966 endingPage "668" @default.
• W2060694966 startingPage "655" @default.
• W2060694966 abstract "The neuronal distribution of cannabinoid receptor in the adult rat brain is reported, combining receptor binding radioautography using the synthetic psychoactive cannabinoid ligand CP55,940 with in situ hybridization histochemistry using oligonucleotide probes complementary to rat cannabinoid receptor cDNA. In the cerebral cortex, especially in the frontal and cingulate cortex, dense binding was found in layers I and VI together with slight mRNA levels in a majority of both pyramidal and non-pyramidal-shaped neurons and of high mRNA levels in a moderate number of non-pyramidal-shaped neurons especially in layers II-III and V-VI. In the hippocampal dentate gyrus, very dense staining was found in the molecular layer together with high mRNA levels in a moderate number of hilar neurons close to the granular layer. In Ammon's horn, especially in the CA3 sector, very dense binding was found in the dendritic layers together with slight mRNA levels in the majority of the pyramidal cells and high mRNA levels in a moderate number of interneurons. In the basal ganglia, binding was very dense in the lateral putamen, substantia nigra pars reticulata, globus pallidus and entopeduncular nucleus, moderate in the medial putamen and caudate; and slight in the accumbens, together with slight to moderate mRNA levels in the striatal medium-sized neurons. Together with slight binding, slight to moderate mRNA levels were found in the majority of the neurons in the subthalamic nucleus. No binding and mRNA were found in the substantia nigra pars compacta and ventral tegmental area. Slight to moderate binding was found together with slight to moderate mRNA levels in the majority of neurons in the anterior olfactory nucleus; septum, especially medial septum and diagonal band of Broca; amygdala, especially basolateral amygdala; lateral habenula; ventromedial hypothalamic nucleus; lateral interpeduncular nucleus; central gray, dorsal cochlear nucleus; parabrachial nucleus; dorsal pontine tegmentum; pontine nuclei; commissural part of the nucleus tractus solitarius; inferior olive and dorsal horn of the spinal cord. In the cerebellum, very dense binding was found in the molecular layer together with slight mRNA levels in the majority of the granule cells and moderate mRNA levels in the basket and stellate cells. In conclusion, this study provides, for the first time, indirect assessment of the neurons containing cannabinoid receptor in the entire adult rat brain and will serve as a basis for future direct morphological confirmation using receptor immunohistochemistry and for functional studies." @default.
• W2060694966 created "2016-06-24" @default.
• W2060694966 creator A5037974528 @default.
• W2060694966 creator A5072347121 @default.
• W2060694966 date "1992-06-01" @default.
• W2060694966 modified "2023-09-28" @default.
• W2060694966 title "Distribution of neuronal cannabinoid receptor in the adult rat brain: A comparative receptor binding radioautography and in situ hybridization histochemistry" @default.
• W2060694966 cites W1836729582 @default.
• W2060694966 cites W1966092598 @default.
• W2060694966 cites W1970971758 @default.
• W2060694966 cites W1979118662 @default.
• W2060694966 cites W1980826175 @default.
• W2060694966 cites W1989481543 @default.
• W2060694966 cites W1991603311 @default.
• W2060694966 cites W2001082387 @default.
• W2060694966 cites W2002240263 @default.
• W2060694966 cites W2008149677 @default.
• W2060694966 cites W2022752214 @default.
• W2060694966 cites W2030905853 @default.
• W2060694966 cites W2040051923 @default.
• W2060694966 cites W2041697634 @default.
• W2060694966 cites W2060772714 @default.
• W2060694966 cites W2075894678 @default.
• W2060694966 cites W2076635082 @default.
• W2060694966 cites W2080383348 @default.
• W2060694966 cites W2085064923 @default.
• W2060694966 cites W2089150464 @default.
• W2060694966 cites W2095217951 @default.
• W2060694966 cites W2120125170 @default.
• W2060694966 cites W4300807653 @default.
• W2060694966 doi "https://doi.org/10.1016/0306-4522(92)90409-u" @default.
• W2060694966 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1376455" @default.
• W2060694966 hasPublicationYear "1992" @default.
• W2060694966 type Work @default.
• W2060694966 sameAs 2060694966 @default.
• W2060694966 citedByCount "626" @default.
• W2060694966 countsByYear W20606949662012 @default.
• W2060694966 countsByYear W20606949662013 @default.
• W2060694966 countsByYear W20606949662014 @default.
• W2060694966 countsByYear W20606949662015 @default.
• W2060694966 countsByYear W20606949662016 @default.
• W2060694966 countsByYear W20606949662017 @default.
• W2060694966 countsByYear W20606949662018 @default.
• W2060694966 countsByYear W20606949662019 @default.
• W2060694966 countsByYear W20606949662020 @default.
• W2060694966 countsByYear W20606949662021 @default.
• W2060694966 countsByYear W20606949662022 @default.
• W2060694966 countsByYear W20606949662023 @default.
• W2060694966 crossrefType "journal-article" @default.
• W2060694966 hasAuthorship W2060694966A5037974528 @default.
• W2060694966 hasAuthorship W2060694966A5072347121 @default.
• W2060694966 hasConcept C104317684 @default.
• W2060694966 hasConcept C105580179 @default.
• W2060694966 hasConcept C126322002 @default.
• W2060694966 hasConcept C134018914 @default.
• W2060694966 hasConcept C137183658 @default.
• W2060694966 hasConcept C148762608 @default.
• W2060694966 hasConcept C169760540 @default.
• W2060694966 hasConcept C2776464000 @default.
• W2060694966 hasConcept C2776552330 @default.
• W2060694966 hasConcept C2776773494 @default.
• W2060694966 hasConcept C2777186548 @default.
• W2060694966 hasConcept C2778187257 @default.
• W2060694966 hasConcept C2778499278 @default.
• W2060694966 hasConcept C2779305214 @default.
• W2060694966 hasConcept C2779714222 @default.
• W2060694966 hasConcept C2780278869 @default.
• W2060694966 hasConcept C2780938664 @default.
• W2060694966 hasConcept C2781134066 @default.
• W2060694966 hasConcept C513476851 @default.
• W2060694966 hasConcept C529278444 @default.
• W2060694966 hasConcept C55493867 @default.
• W2060694966 hasConcept C71924100 @default.
• W2060694966 hasConcept C81439078 @default.
• W2060694966 hasConcept C86803240 @default.
• W2060694966 hasConceptScore W2060694966C104317684 @default.
• W2060694966 hasConceptScore W2060694966C105580179 @default.
• W2060694966 hasConceptScore W2060694966C126322002 @default.
• W2060694966 hasConceptScore W2060694966C134018914 @default.
• W2060694966 hasConceptScore W2060694966C137183658 @default.
• W2060694966 hasConceptScore W2060694966C148762608 @default.
• W2060694966 hasConceptScore W2060694966C169760540 @default.
• W2060694966 hasConceptScore W2060694966C2776464000 @default.
• W2060694966 hasConceptScore W2060694966C2776552330 @default.
• W2060694966 hasConceptScore W2060694966C2776773494 @default.
• W2060694966 hasConceptScore W2060694966C2777186548 @default.
• W2060694966 hasConceptScore W2060694966C2778187257 @default.
• W2060694966 hasConceptScore W2060694966C2778499278 @default.
• W2060694966 hasConceptScore W2060694966C2779305214 @default.
• W2060694966 hasConceptScore W2060694966C2779714222 @default.
• W2060694966 hasConceptScore W2060694966C2780278869 @default.
• W2060694966 hasConceptScore W2060694966C2780938664 @default.
• W2060694966 hasConceptScore W2060694966C2781134066 @default.
• W2060694966 hasConceptScore W2060694966C513476851 @default.
• W2060694966 hasConceptScore W2060694966C529278444 @default.
• W2060694966 hasConceptScore W2060694966C55493867 @default.
• W2060694966 hasConceptScore W2060694966C71924100 @default.
• W2060694966 hasConceptScore W2060694966C81439078 @default.

• next