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- W2060714044 abstract "Bladder cancer screening faces several obstacles, including low yield, numerous false-positive results, and the absence of a single effective screening test. We present a model of a screening program that (1) targets an occupational cohort exposed to a putative carcinogen, to increase the detection of disease, (2) uses four screening tests in parallel to maximize case detection, and (3) defines a diagnostic protocol that minimizes the number of invasive procedures by utilizing both flexible and rigid cystoscopy. In a hypothetical cohort of 1000 men aged 45 to 74 years potentially exposed to a bladder carcinogen, the model would find eight of the nine detectable cancers, with a sensitivity of 89% and a specificity of 78%. In addition, the model allows the sensitivities, specificities, and predictive values of the individual screening tests to be compared and evaluated in a single cohort." @default.
- W2060714044 created "2016-06-24" @default.
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- W2060714044 date "1990-09-01" @default.
- W2060714044 modified "2023-10-15" @default.
- W2060714044 title "Advances in Screening Protocols for the Detection of Early Bladder Cancer" @default.
- W2060714044 doi "https://doi.org/10.1097/00043764-199009000-00036" @default.
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