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- W2060716117 abstract "Background: The consequences of the electrical discharge over the myocardiumin patients with implantable cardioverter-defibrillator (ICD) is continuously debated and its implications are controversial Cardiac troponin T (cTnT) elevations have been reported to occur after discharges, the relation between cTnT elevation after ICD firing and patients co-morbidity is still to be established. We aim to evaluate the outcome of heart failure patients with elevated cTnT after ICD discharge to establish its utility as a prognostic factor. Methods: This is a retrospective observational study comprised of 155 patients (mean (SD) age 61 (15) years, 45 women) who were admitted to our institution after receiving spontaneous (n = 57) ICD discharges were studied. cTnT was measured between 12 and 24 h after ICD discharge. The relationship between cTnT levels and all-cause mortality was assessed in univariate and multivariate analyses. Results: During a median follow-up period of 66 months, 38 (24%) patients died. Patients with a post-discharge cTnT level of >0.12 ng/ml had worse survival than those with cTnT <0.12 ng/ml. Using adjusted Cox multivariate analysis for older age, history of diabetes, heart failure exacerbation and hypertension raised cTnT remained the most significant predictor of mortality. Conclusions: Elevation of cTnT after ICD discharge, particularly in patient admitted with heart failure, is a risk factor for mortality that is independent of other common clinical factors that predict survival in such patients." @default.
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- W2060716117 date "2010-08-01" @default.
- W2060716117 modified "2023-10-16" @default.
- W2060716117 title "Heart Failure Patients Admitted With Elevated Cardiac Troponin Post Implantable Cardioverter-Defibrillator Firing Carry the Highest Mortality Rates" @default.
- W2060716117 doi "https://doi.org/10.1016/j.cardfail.2010.06.206" @default.
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