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• W2060752803 abstract "(−)DRF 2725 (6) is a phenoxazine analogue of phenyl propanoic acid. Compound 6 showed interesting dual activation of PPARα and PPARγ. In insulin resistant db/db mice, 6 showed better reduction of plasma glucose and triglyceride levels as compared to rosiglitazone. Compound 6 has also shown good oral bioavailability and impressive pharmacokinetic characteristics. Our study indicates that 6 has great potential as a drug for diabetes and dyslipidemia." @default.
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• W2060752803 date "2001-07-11" @default.
• W2060752803 modified "2023-10-04" @default.
• W2060752803 title "(−)3-[4-[2-(Phenoxazin-10-yl)ethoxy]phenyl]-2-ethoxypropanoic Acid [(−)DRF 2725]: A Dual PPAR Agonist with Potent Antihyperglycemic and Lipid Modulating Activity" @default.
• W2060752803 cites W1976766119 @default.
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• W2060752803 doi "https://doi.org/10.1021/jm010143b" @default.
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