FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060755144> ?p ?o ?g. }

• W2060755144 endingPage "14" @default.
• W2060755144 startingPage "6" @default.
• W2060755144 abstract "Contemporary infant cardiopulmonary bypass circuits require a blood prime. Blood, especially when stored, generates an inflammatory response, and may contribute to organ dysfunction following cardiopulmonary bypass. We determined whether using a miniaturized circuit and an asanguineous prime attenuated the post-bypass inflammatory response, and improved right ventricular and pulmonary function.Sixteen infant piglets were placed into 3 groups based on prime components: group I (fresh blood), group II (stored blood), and group III (miniaturized circuit and asanguineous prime). Piglets were placed on cardiopulmonary bypass (100 mL.kg(-1).min(-1)), cooled to 18 degrees C, and underwent continuous perfusion (50 mL.kg(-1).min(-1)) for 30 minutes. They were rewarmed and separated from bypass. Serum tumor necrosis factor-alpha, right ventricular function, and pulmonary function were measured before and 30 minutes after bypass. Neutrophil priming activity in fresh and stored donor blood was also assessed.Animals in group III had significantly improved cardiopulmonary function than the groups receiving blood (right ventricular cardiac index [mL.kg(-1).min(-1)]: group I [18.8 +/- 4.8], group II [21.5 +/- 6.2], and group III [81.2 +/- 11.4], p < 0.001; and pulmonary vascular resistance index [dynes.mL(-1).kg(-1)]: group I [1169 +/- 409], group II [1610 +/- 486], and group III [214 +/- 63], p = 0.03). Tumor necrosis factor-alpha (pg.mL(-1)) was lower in group III (1465 +/- 39) than in the groups receiving blood (3940 +/- 777), p = 0.002. Neutrophil priming activity (nmol.min(-1)) was also higher in stored blood (3.7 +/- 6) than in fresh blood (1.9 +/- 0.2), p = 0.02.We have devised a unique miniaturized circuit that allows an asanguineous prime without hemodilution in an infant swine model. The employment of this circuit attenuates the post-bypass inflammatory response and has salutary effects on cardiopulmonary function." @default.
• W2060755144 created "2016-06-24" @default.
• W2060755144 creator A5009816972 @default.
• W2060755144 creator A5012813357 @default.
• W2060755144 creator A5032890276 @default.
• W2060755144 creator A5056714303 @default.
• W2060755144 creator A5058696312 @default.
• W2060755144 creator A5072897727 @default.
• W2060755144 creator A5084957376 @default.
• W2060755144 date "2005-07-01" @default.
• W2060755144 modified "2023-10-14" @default.
• W2060755144 title "Using a Miniaturized Circuit and an Asanguineous Prime to Reduce Neutrophil-Mediated Organ Dysfunction Following Infant Cardiopulmonary Bypass" @default.
• W2060755144 cites W1968507156 @default.
• W2060755144 cites W1975200129 @default.
• W2060755144 cites W1985211728 @default.
• W2060755144 cites W1992458520 @default.
• W2060755144 cites W1994965038 @default.
• W2060755144 cites W1996760444 @default.
• W2060755144 cites W1996892977 @default.
• W2060755144 cites W1999613791 @default.
• W2060755144 cites W2000007666 @default.
• W2060755144 cites W2006103263 @default.
• W2060755144 cites W2013041517 @default.
• W2060755144 cites W2021849468 @default.
• W2060755144 cites W2041120347 @default.
• W2060755144 cites W2051755430 @default.
• W2060755144 cites W2053542090 @default.
• W2060755144 cites W2055043687 @default.
• W2060755144 cites W2057769241 @default.
• W2060755144 cites W2074002458 @default.
• W2060755144 cites W2075692244 @default.
• W2060755144 cites W2076685425 @default.
• W2060755144 cites W2077637580 @default.
• W2060755144 cites W2085876854 @default.
• W2060755144 cites W2089322543 @default.
• W2060755144 cites W2092498025 @default.
• W2060755144 cites W2105392629 @default.
• W2060755144 cites W2111403445 @default.
• W2060755144 cites W2116957157 @default.
• W2060755144 cites W2139468334 @default.
• W2060755144 cites W2151525655 @default.
• W2060755144 cites W2169417312 @default.
• W2060755144 cites W2341630418 @default.
• W2060755144 doi "https://doi.org/10.1016/j.athoracsur.2005.02.030" @default.
• W2060755144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15975331" @default.
• W2060755144 hasPublicationYear "2005" @default.
• W2060755144 type Work @default.
• W2060755144 sameAs 2060755144 @default.
• W2060755144 citedByCount "44" @default.
• W2060755144 countsByYear W20607551442012 @default.
• W2060755144 countsByYear W20607551442013 @default.
• W2060755144 countsByYear W20607551442014 @default.
• W2060755144 countsByYear W20607551442016 @default.
• W2060755144 countsByYear W20607551442018 @default.
• W2060755144 countsByYear W20607551442019 @default.
• W2060755144 countsByYear W20607551442021 @default.
• W2060755144 countsByYear W20607551442022 @default.
• W2060755144 countsByYear W20607551442023 @default.
• W2060755144 crossrefType "journal-article" @default.
• W2060755144 hasAuthorship W2060755144A5009816972 @default.
• W2060755144 hasAuthorship W2060755144A5012813357 @default.
• W2060755144 hasAuthorship W2060755144A5032890276 @default.
• W2060755144 hasAuthorship W2060755144A5056714303 @default.
• W2060755144 hasAuthorship W2060755144A5058696312 @default.
• W2060755144 hasAuthorship W2060755144A5072897727 @default.
• W2060755144 hasAuthorship W2060755144A5084957376 @default.
• W2060755144 hasBestOaLocation W20607551441 @default.
• W2060755144 hasConcept C100701293 @default.
• W2060755144 hasConcept C126322002 @default.
• W2060755144 hasConcept C146957229 @default.
• W2060755144 hasConcept C178853913 @default.
• W2060755144 hasConcept C17991360 @default.
• W2060755144 hasConcept C2778881276 @default.
• W2060755144 hasConcept C42219234 @default.
• W2060755144 hasConcept C58245268 @default.
• W2060755144 hasConcept C59822182 @default.
• W2060755144 hasConcept C71924100 @default.
• W2060755144 hasConcept C75603125 @default.
• W2060755144 hasConcept C81444415 @default.
• W2060755144 hasConcept C86803240 @default.
• W2060755144 hasConceptScore W2060755144C100701293 @default.
• W2060755144 hasConceptScore W2060755144C126322002 @default.
• W2060755144 hasConceptScore W2060755144C146957229 @default.
• W2060755144 hasConceptScore W2060755144C178853913 @default.
• W2060755144 hasConceptScore W2060755144C17991360 @default.
• W2060755144 hasConceptScore W2060755144C2778881276 @default.
• W2060755144 hasConceptScore W2060755144C42219234 @default.
• W2060755144 hasConceptScore W2060755144C58245268 @default.
• W2060755144 hasConceptScore W2060755144C59822182 @default.
• W2060755144 hasConceptScore W2060755144C71924100 @default.
• W2060755144 hasConceptScore W2060755144C75603125 @default.
• W2060755144 hasConceptScore W2060755144C81444415 @default.
• W2060755144 hasConceptScore W2060755144C86803240 @default.
• W2060755144 hasIssue "1" @default.
• W2060755144 hasLocation W20607551441 @default.
• W2060755144 hasLocation W20607551442 @default.
• W2060755144 hasOpenAccess W2060755144 @default.
• W2060755144 hasPrimaryLocation W20607551441 @default.

• next