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- W2060758906 abstract "To evaluate the acute and chronic blood pressure (BP) response after renal artery stent implantation, we prospectively studied 39 patients (14 men, 25 women, mean age = 67 ± 1O) with hypertension (HTN) refractory to medical therapy and atherosclerotic renal artery stenosis ≥70%) who were treated with balloon angioplasty and deployment of a stainless steel, non-articulated, balloon expandable Palmaz stent. Twenty three (59%) patients had unilateral stenosis, 14 (36%) had bilateral disease, and 2 (5%) had a solitary kidney. The mean number of anti-hypertensive medications was 2.5 before treatment. BP was recorded at baseline, 24 hrs., and at 1, 3, and 6 months after stent implantation. Patients were classified either as responders (R), defined as a ≥15% drop in systolic (SBP) and/or diastolic blood pressure (DBP) from baseline Bp, or non-responders (NR) based on their 6 month BP result. Systolic Blood PressureEmpty CellNBaseline24 hr1 mo6 moTotal cohort39177 ± 22138 ± 20*158 ± 30**152 ± 25*Responders (R)25184 ± 22140 ± 23*160 ± 32*143 ± 21*Non-responders (NR)14166 ± 19134 ± 11*157 ± 30167 ± 25*p < 0.0001**p < 0.001 versus baseline BP p < 0.0001 p < 0.001 versus baseline BP A significant (≥15%) improvement in SBP and/or DBP was measured in 86% of all patients 24 hours after stent implantation. At one and 6 months, 63% had sustained improvement in both SBP and DBP and were long-term responders. A sustained BP improvement 6 months after stenting was predicted by older patient age, more severe hypertension, and larger reference vessel diameter (p < 0.05). Not predictive of a favorable response to stenting was sex, number of HTN medications, unilateral versus bilateral disease, baseline serum Cr, BUN, or 6 month angiographic (≥50% diameter) restenosis. Renal artery stenting results in immediate BP control in the majority patients studied, however, this BP improvement is sustained in only 63% of patients. Multi-variant analysis indicates that older patients with more severe hypertension and larger renal arteries are more likely to receive a sustained benefit from renal artery stenting." @default.
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- W2060758906 date "1995-02-01" @default.
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- W2060758906 title "796-4 Acute and Long-term Effect of Renal Artery Stenting on Blood Pressure Control In Patients with Atherosclerotic Renovascular Hypertension" @default.
- W2060758906 doi "https://doi.org/10.1016/0735-1097(95)93038-e" @default.
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