Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060879117> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2060879117 endingPage "157" @default.
- W2060879117 startingPage "151" @default.
- W2060879117 abstract "A prospective, randomized, double-blind trial was designed to compare the duration of analgesia produced by intravenous morphine and methadone. Patients with intractable cancer-related pain were studied for 5–6 days. One-eighth of the patient's daily opiate requirement was supplied as an i.v. infusion of either morphine or methadone over a period of 15 min, when initiated by the patient using a patient-controlled analgesia device. Dosing intervals, pain intensity assessments and toxicity were evaluated. Twenty-three patients were randomized; 18 were fully evaluable. Ten of the evaluable patients received morphine, 8 received methadone. Dosing intervals did not change over the 5 days for either group. The mean dosing interval for the last 10 doses was 3.9 ± 0.85 h for patients receiving morphine and 3.9 ± 1.6 h for patients receiving methadone (P = NS). One patient receiving morphine and one taking methadone required only 2–3 doses/day for pain control. Pain intensity and relief were similar for both groups. All patients had adequate analgesia as determined by at least a 50% difference in pain intensity at peak relief. The duration of pain relief when repeated intravenous doses of these analgesics were given was similar throughout the entire study period although morphine and methadone have different serum half-lives (3 vs. 25 h). Parenteral methadone does not offer a clinically significant increase in the duration of analgesia in patients with severe pain secondary to cancer." @default.
- W2060879117 created "2016-06-24" @default.
- W2060879117 creator A5003214440 @default.
- W2060879117 creator A5003800142 @default.
- W2060879117 creator A5010420312 @default.
- W2060879117 creator A5056660736 @default.
- W2060879117 creator A5068669331 @default.
- W2060879117 date "1989-08-01" @default.
- W2060879117 modified "2023-09-26" @default.
- W2060879117 title "Does intravenous methadone provide longer lasting analgesia than intravenous morphine? A randomized, double-blind study" @default.
- W2060879117 cites W1847168837 @default.
- W2060879117 cites W1983942083 @default.
- W2060879117 cites W2039382400 @default.
- W2060879117 cites W2041285354 @default.
- W2060879117 cites W2049734416 @default.
- W2060879117 cites W2070257919 @default.
- W2060879117 cites W2072255226 @default.
- W2060879117 cites W2074408303 @default.
- W2060879117 cites W2084518320 @default.
- W2060879117 cites W2093512375 @default.
- W2060879117 cites W2316803987 @default.
- W2060879117 cites W33046746 @default.
- W2060879117 doi "https://doi.org/10.1016/0304-3959(89)90233-9" @default.
- W2060879117 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2488674" @default.
- W2060879117 hasPublicationYear "1989" @default.
- W2060879117 type Work @default.
- W2060879117 sameAs 2060879117 @default.
- W2060879117 citedByCount "53" @default.
- W2060879117 countsByYear W20608791172013 @default.
- W2060879117 countsByYear W20608791172014 @default.
- W2060879117 countsByYear W20608791172017 @default.
- W2060879117 countsByYear W20608791172018 @default.
- W2060879117 countsByYear W20608791172020 @default.
- W2060879117 countsByYear W20608791172021 @default.
- W2060879117 countsByYear W20608791172022 @default.
- W2060879117 countsByYear W20608791172023 @default.
- W2060879117 crossrefType "journal-article" @default.
- W2060879117 hasAuthorship W2060879117A5003214440 @default.
- W2060879117 hasAuthorship W2060879117A5003800142 @default.
- W2060879117 hasAuthorship W2060879117A5010420312 @default.
- W2060879117 hasAuthorship W2060879117A5056660736 @default.
- W2060879117 hasAuthorship W2060879117A5068669331 @default.
- W2060879117 hasConcept C121608353 @default.
- W2060879117 hasConcept C126322002 @default.
- W2060879117 hasConcept C141071460 @default.
- W2060879117 hasConcept C168563851 @default.
- W2060879117 hasConcept C170493617 @default.
- W2060879117 hasConcept C2777288759 @default.
- W2060879117 hasConcept C2777389121 @default.
- W2060879117 hasConcept C2778140631 @default.
- W2060879117 hasConcept C2778767360 @default.
- W2060879117 hasConcept C2778904085 @default.
- W2060879117 hasConcept C2781063702 @default.
- W2060879117 hasConcept C42219234 @default.
- W2060879117 hasConcept C71924100 @default.
- W2060879117 hasConceptScore W2060879117C121608353 @default.
- W2060879117 hasConceptScore W2060879117C126322002 @default.
- W2060879117 hasConceptScore W2060879117C141071460 @default.
- W2060879117 hasConceptScore W2060879117C168563851 @default.
- W2060879117 hasConceptScore W2060879117C170493617 @default.
- W2060879117 hasConceptScore W2060879117C2777288759 @default.
- W2060879117 hasConceptScore W2060879117C2777389121 @default.
- W2060879117 hasConceptScore W2060879117C2778140631 @default.
- W2060879117 hasConceptScore W2060879117C2778767360 @default.
- W2060879117 hasConceptScore W2060879117C2778904085 @default.
- W2060879117 hasConceptScore W2060879117C2781063702 @default.
- W2060879117 hasConceptScore W2060879117C42219234 @default.
- W2060879117 hasConceptScore W2060879117C71924100 @default.
- W2060879117 hasIssue "2" @default.
- W2060879117 hasLocation W20608791171 @default.
- W2060879117 hasLocation W20608791172 @default.
- W2060879117 hasOpenAccess W2060879117 @default.
- W2060879117 hasPrimaryLocation W20608791171 @default.
- W2060879117 hasRelatedWork W1837738291 @default.
- W2060879117 hasRelatedWork W2000801346 @default.
- W2060879117 hasRelatedWork W2060879117 @default.
- W2060879117 hasRelatedWork W2075267799 @default.
- W2060879117 hasRelatedWork W2142613079 @default.
- W2060879117 hasRelatedWork W2155437609 @default.
- W2060879117 hasRelatedWork W2587011781 @default.
- W2060879117 hasRelatedWork W3181681555 @default.
- W2060879117 hasRelatedWork W4295106475 @default.
- W2060879117 hasRelatedWork W98909232 @default.
- W2060879117 hasVolume "38" @default.
- W2060879117 isParatext "false" @default.
- W2060879117 isRetracted "false" @default.
- W2060879117 magId "2060879117" @default.
- W2060879117 workType "article" @default.