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• W2060898534 abstract "Abstract The indirect immunoperoxidase technique was used to demonstrate the presence of cytochrome P -450 isozymes (5 and 8), NADPH cytochrome c reductase and epoxide hydratase in adult human hepatocytes cultured alone or co-cultured with rat-liver epithelial cells for 1–15 days. The results showed that several drug-metabolizing enzymes were well maintained for at least 2 wk in human hepatocyte cultures. In addition, cytochrome P -450-5 was found to be heterogeneously distributed in cultured cells, thus reflecting the uneven distribution observed in the liver in vivo ." @default.
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• W2060898534 date "1986-06-01" @default.
• W2060898534 modified "2023-09-25" @default.
• W2060898534 title "Immunocytochemical evidence for the maintenance of cytochrome P-450 isozymes, NADPH cytochrome c reductase and epoxide hydratase in pure and mixed primary cultures of adult human hepatocytes" @default.
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• W2060898534 doi "https://doi.org/10.1016/0278-6915(86)90120-1" @default.
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