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- W2060922840 abstract "Sixteen healthy volunteers of a mean age of x = 26.4 years took part in a driving simulator test in an eightfold crossover study under double-blind conditions. The additonal influence of alcohol was tested acutely after a single administration of 2mg lormetazepam, a new, highly effective derivative from the benzodiazepine class, 10 mg mepindolol sulphate, a new betablocker without sedating properties, and 10mg diazepam. All drugs were compared with placebo and the test was performed 1, 2 and 3 hours after oral intake. The aim was to investigate particularly the risks relevant in road traffic caused by simultaneous intake of these substances with alcohol. For this purpose, besides the driving simulator, an accurate reaction test (WDG) and self-rating scales were used, the latter in order to assess subjective stress and anxiety levels." @default.
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- W2060922840 date "1984-03-01" @default.
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- W2060922840 title "Alcohol Interaction of Lormetazepam, Mepindolol Sulphate and Diazepam Measured by Performance on the Driving Simulator" @default.
- W2060922840 doi "https://doi.org/10.1055/s-2007-1017405" @default.
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