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• W2060935625 abstract "Ultrastructural evidence is presented for the presence of membrane-bound glucocorticoid recognition and binding sites. Corticosterone was derivatized at 3 different positions and coupled covalently to bovine serum albumin (BSA). All three derivatives competed for binding of [3H]corticosterone by isolated rat hepatocytes. The most effective competitor, corticosterone-succinate-BSA (CSB), was adsorbed onto colloidal gold particles (CSB-gold, 17 +/- 3 nm dia). When isolated rat hepatocytes or mouse pituitary tumor cells (AtT 20) are incubated with CSB-gold, specific binding in the microvilli-rich region of these cells is seen. This binding of CSB-gold is reduced by about 50% in the presence of unlabelled CSB or corticosterone." @default.
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• W2060935625 date "1991-09-01" @default.
• W2060935625 modified "2023-10-16" @default.
• W2060935625 title "Electron microscopic demonstration of glucocorticoid recognition sites on isolated rat hepatocytes" @default.
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• W2060935625 doi "https://doi.org/10.1016/0960-0760(91)90041-3" @default.
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