Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060952981> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2060952981 endingPage "167" @default.
- W2060952981 startingPage "147" @default.
- W2060952981 abstract "E.P.R. spin trapping has been employed to study radical production during the bactericidal action of three peroxide compounds (peracetic acid, 4-percarboxy-N-isobutyltrimellitimide and magnesium monoperoxyphthalate) upon both Gram negative (Escherichia Coll) and Gram positive (Staphylococcus Aureus) bacteria. Use of the spin trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO) has allowed direct detection of both carbon-centred and hydroxyl radicals, which are produced at varying rates for the different bacteria/peracid systems studied. The inhibition of bactericidal action, by DMPO and two antioxidants, Vitamin C and Trolox C, indicates that radicals are the lethal species and evidence is presented which suggests that radical production is internal to the bacterial cell. Hydroxyl radicals are believed to be the lethal species. The effect of added iron chelators and haem protein inhibitors indicates that iron species and haem proteins in particular are involved. A marked variation is found in observed hydroxyl-radical adduct signals with both the nature and concentration of peracid. A strong inverse correlation is found between the concentration of the observed radical adduct signal and the relative strength of the peroxide as a bactericide; use of a stable nitroxide as a radical scavenger confirms that strong bactericides produce radicals at a much faster rate than weak bactericides. Plots of radical generation versus time are correlated with % bacterial kill, offering further evidence that hydroxyl radicals are the lethal species." @default.
- W2060952981 created "2016-06-24" @default.
- W2060952981 creator A5002879351 @default.
- W2060952981 creator A5069317976 @default.
- W2060952981 creator A5086074248 @default.
- W2060952981 creator A5072960067 @default.
- W2060952981 date "1994-01-01" @default.
- W2060952981 modified "2023-09-23" @default.
- W2060952981 title "The Bactericidal Action of Peroxides; An E.P.R. Spin-Trapping Study" @default.
- W2060952981 cites W1444271771 @default.
- W2060952981 cites W1983198076 @default.
- W2060952981 cites W1995340760 @default.
- W2060952981 cites W2009383751 @default.
- W2060952981 cites W2024921655 @default.
- W2060952981 cites W2028585334 @default.
- W2060952981 cites W2058647574 @default.
- W2060952981 cites W2122364936 @default.
- W2060952981 doi "https://doi.org/10.3109/10715769409056566" @default.
- W2060952981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7981786" @default.
- W2060952981 hasPublicationYear "1994" @default.
- W2060952981 type Work @default.
- W2060952981 sameAs 2060952981 @default.
- W2060952981 citedByCount "38" @default.
- W2060952981 countsByYear W20609529812012 @default.
- W2060952981 countsByYear W20609529812013 @default.
- W2060952981 countsByYear W20609529812015 @default.
- W2060952981 countsByYear W20609529812016 @default.
- W2060952981 countsByYear W20609529812018 @default.
- W2060952981 countsByYear W20609529812019 @default.
- W2060952981 countsByYear W20609529812020 @default.
- W2060952981 countsByYear W20609529812021 @default.
- W2060952981 countsByYear W20609529812022 @default.
- W2060952981 countsByYear W20609529812023 @default.
- W2060952981 crossrefType "journal-article" @default.
- W2060952981 hasAuthorship W2060952981A5002879351 @default.
- W2060952981 hasAuthorship W2060952981A5069317976 @default.
- W2060952981 hasAuthorship W2060952981A5072960067 @default.
- W2060952981 hasAuthorship W2060952981A5086074248 @default.
- W2060952981 hasConcept C108204754 @default.
- W2060952981 hasConcept C139066938 @default.
- W2060952981 hasConcept C178790620 @default.
- W2060952981 hasConcept C185592680 @default.
- W2060952981 hasConcept C2776231299 @default.
- W2060952981 hasConcept C2776778087 @default.
- W2060952981 hasConcept C2777309684 @default.
- W2060952981 hasConcept C2778004101 @default.
- W2060952981 hasConcept C2778815226 @default.
- W2060952981 hasConcept C2781048764 @default.
- W2060952981 hasConcept C2781401929 @default.
- W2060952981 hasConcept C523546767 @default.
- W2060952981 hasConcept C533411734 @default.
- W2060952981 hasConcept C54355233 @default.
- W2060952981 hasConcept C55493867 @default.
- W2060952981 hasConcept C75473681 @default.
- W2060952981 hasConcept C86803240 @default.
- W2060952981 hasConceptScore W2060952981C108204754 @default.
- W2060952981 hasConceptScore W2060952981C139066938 @default.
- W2060952981 hasConceptScore W2060952981C178790620 @default.
- W2060952981 hasConceptScore W2060952981C185592680 @default.
- W2060952981 hasConceptScore W2060952981C2776231299 @default.
- W2060952981 hasConceptScore W2060952981C2776778087 @default.
- W2060952981 hasConceptScore W2060952981C2777309684 @default.
- W2060952981 hasConceptScore W2060952981C2778004101 @default.
- W2060952981 hasConceptScore W2060952981C2778815226 @default.
- W2060952981 hasConceptScore W2060952981C2781048764 @default.
- W2060952981 hasConceptScore W2060952981C2781401929 @default.
- W2060952981 hasConceptScore W2060952981C523546767 @default.
- W2060952981 hasConceptScore W2060952981C533411734 @default.
- W2060952981 hasConceptScore W2060952981C54355233 @default.
- W2060952981 hasConceptScore W2060952981C55493867 @default.
- W2060952981 hasConceptScore W2060952981C75473681 @default.
- W2060952981 hasConceptScore W2060952981C86803240 @default.
- W2060952981 hasIssue "3" @default.
- W2060952981 hasLocation W20609529811 @default.
- W2060952981 hasLocation W20609529812 @default.
- W2060952981 hasOpenAccess W2060952981 @default.
- W2060952981 hasPrimaryLocation W20609529811 @default.
- W2060952981 hasRelatedWork W1481688102 @default.
- W2060952981 hasRelatedWork W1520525278 @default.
- W2060952981 hasRelatedWork W2013092744 @default.
- W2060952981 hasRelatedWork W2055641262 @default.
- W2060952981 hasRelatedWork W2058143492 @default.
- W2060952981 hasRelatedWork W2060952981 @default.
- W2060952981 hasRelatedWork W2075503866 @default.
- W2060952981 hasRelatedWork W2334419558 @default.
- W2060952981 hasRelatedWork W2382067821 @default.
- W2060952981 hasRelatedWork W2494333555 @default.
- W2060952981 hasVolume "21" @default.
- W2060952981 isParatext "false" @default.
- W2060952981 isRetracted "false" @default.
- W2060952981 magId "2060952981" @default.
- W2060952981 workType "article" @default.