FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060996895> ?p ?o ?g. }

• W2060996895 endingPage "137" @default.
• W2060996895 startingPage "129" @default.
• W2060996895 abstract "The overexpression of osteopontin is associated with various inflammatory liver diseases. Interestingly, each of these diseases is also associated with IL-17 expression. Therefore, we sought to determine whether there is any mechanistic link between osteopontin and IL-17. Herein we show that IL-17 and osteopontin levels were significantly increased in patients with chronic hepatitis B. We found that IL-17 and osteopontin levels increased similarly in mice with concanavalin A-induced hepatitis. Both osteopontin- and IL-17-deficient mice were resistant to concanavalin A-induced hepatic injury. In addition, osteopontin markedly induced IL-17 expression by leukocytes (from humans and mice). This effect could be blocked by a specific antibody against osteopontin. β3 integrin (one of the osteopontin receptors) was critically involved in the induction of IL-17 production by osteopontin. Osteopontin-induced IL-17 expression was mediated through the p38, JNK, and NF-κB pathways. These findings suggest that osteopontin regulates IL-17 production during the pathogenesis of hepatitis and provide new evidence for the critical roles of osteopontin and IL-17 in hepatitis." @default.
• W2060996895 created "2016-06-24" @default.
• W2060996895 creator A5002881006 @default.
• W2060996895 creator A5017119373 @default.
• W2060996895 creator A5019529550 @default.
• W2060996895 creator A5027560531 @default.
• W2060996895 creator A5029747713 @default.
• W2060996895 creator A5034603708 @default.
• W2060996895 creator A5048752244 @default.
• W2060996895 creator A5054898080 @default.
• W2060996895 creator A5057422995 @default.
• W2060996895 creator A5060010227 @default.
• W2060996895 creator A5074919264 @default.
• W2060996895 date "2012-10-01" @default.
• W2060996895 modified "2023-10-02" @default.
• W2060996895 title "Osteopontin regulates interleukin-17 production in hepatitis" @default.
• W2060996895 cites W1856085327 @default.
• W2060996895 cites W1903810524 @default.
• W2060996895 cites W1972264612 @default.
• W2060996895 cites W1974259787 @default.
• W2060996895 cites W1986904544 @default.
• W2060996895 cites W1987722154 @default.
• W2060996895 cites W2002786924 @default.
• W2060996895 cites W2004186675 @default.
• W2060996895 cites W2006249161 @default.
• W2060996895 cites W2006877529 @default.
• W2060996895 cites W2010939329 @default.
• W2060996895 cites W2015337271 @default.
• W2060996895 cites W2017046428 @default.
• W2060996895 cites W2041537003 @default.
• W2060996895 cites W2044580027 @default.
• W2060996895 cites W2045510035 @default.
• W2060996895 cites W2051175845 @default.
• W2060996895 cites W2054568222 @default.
• W2060996895 cites W2057616292 @default.
• W2060996895 cites W2064342046 @default.
• W2060996895 cites W2079650044 @default.
• W2060996895 cites W2086396801 @default.
• W2060996895 cites W2092289533 @default.
• W2060996895 cites W2097139406 @default.
• W2060996895 cites W2103952088 @default.
• W2060996895 cites W2116734097 @default.
• W2060996895 cites W2133765154 @default.
• W2060996895 cites W2151566115 @default.
• W2060996895 cites W2151838794 @default.
• W2060996895 cites W2155174618 @default.
• W2060996895 cites W2161630702 @default.
• W2060996895 cites W2162055377 @default.
• W2060996895 cites W2170335992 @default.
• W2060996895 cites W2295791300 @default.
• W2060996895 cites W2330826514 @default.
• W2060996895 cites W4229876265 @default.
• W2060996895 cites W4238652665 @default.
• W2060996895 cites W4377077050 @default.
• W2060996895 cites W64278426 @default.
• W2060996895 cites W2276450118 @default.
• W2060996895 doi "https://doi.org/10.1016/j.cyto.2012.06.287" @default.
• W2060996895 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22818182" @default.
• W2060996895 hasPublicationYear "2012" @default.
• W2060996895 type Work @default.
• W2060996895 sameAs 2060996895 @default.
• W2060996895 citedByCount "23" @default.
• W2060996895 countsByYear W20609968952013 @default.
• W2060996895 countsByYear W20609968952014 @default.
• W2060996895 countsByYear W20609968952015 @default.
• W2060996895 countsByYear W20609968952016 @default.
• W2060996895 countsByYear W20609968952018 @default.
• W2060996895 countsByYear W20609968952019 @default.
• W2060996895 countsByYear W20609968952020 @default.
• W2060996895 countsByYear W20609968952021 @default.
• W2060996895 countsByYear W20609968952022 @default.
• W2060996895 countsByYear W20609968952023 @default.
• W2060996895 crossrefType "journal-article" @default.
• W2060996895 hasAuthorship W2060996895A5002881006 @default.
• W2060996895 hasAuthorship W2060996895A5017119373 @default.
• W2060996895 hasAuthorship W2060996895A5019529550 @default.
• W2060996895 hasAuthorship W2060996895A5027560531 @default.
• W2060996895 hasAuthorship W2060996895A5029747713 @default.
• W2060996895 hasAuthorship W2060996895A5034603708 @default.
• W2060996895 hasAuthorship W2060996895A5048752244 @default.
• W2060996895 hasAuthorship W2060996895A5054898080 @default.
• W2060996895 hasAuthorship W2060996895A5057422995 @default.
• W2060996895 hasAuthorship W2060996895A5060010227 @default.
• W2060996895 hasAuthorship W2060996895A5074919264 @default.
• W2060996895 hasConcept C19869320 @default.
• W2060996895 hasConcept C202751555 @default.
• W2060996895 hasConcept C203014093 @default.
• W2060996895 hasConcept C2780804394 @default.
• W2060996895 hasConcept C2780942790 @default.
• W2060996895 hasConcept C55493867 @default.
• W2060996895 hasConcept C71924100 @default.
• W2060996895 hasConcept C86803240 @default.
• W2060996895 hasConceptScore W2060996895C19869320 @default.
• W2060996895 hasConceptScore W2060996895C202751555 @default.
• W2060996895 hasConceptScore W2060996895C203014093 @default.
• W2060996895 hasConceptScore W2060996895C2780804394 @default.
• W2060996895 hasConceptScore W2060996895C2780942790 @default.
• W2060996895 hasConceptScore W2060996895C55493867 @default.

• next