Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061058105> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2061058105 endingPage "335" @default.
- W2061058105 startingPage "331" @default.
- W2061058105 abstract "To review the role of metropolitan endotoxin exposure in asthma and allergy, emphasizing recently published articles (i.e. April 2002-June 2003).In infants and toddlers in metropolitan communities, higher endotoxin levels in house dust are associated with less atopy and increased wheezing in infancy, but this increased risk may normalize by age 4 years. Increased endotoxin levels and exposure in metropolitan households with dogs and sometimes cats is intriguing in light of recent studies suggesting that animal exposure early in life is associated with less allergen sensitization and asthma. Dust endotoxin also appears to serve as a marker for other similar innate immune-stimulatory microbial components called pathogen-associated molecular patterns. Pathogen-associated molecular patterns, such as bacterial DNA, may augment and steer endotoxin-initiated immune responses in an immune-regulatory direction. These findings support the premise that the differences in health outcomes from endotoxin exposure are due to important moderating variables, such as age of exposure, timing of exposure relative to disease development, dose and frequency of exposure, co-exposures, and genetic predispositions in response to endotoxin.We will discuss (1) endotoxin's ability to exacerbate established atopic disease and asthma; (2) factors influencing endotoxin levels in metropolitan homes; (3) relationships between endotoxin, pet exposure, and atopic disease; (4) endotoxin's paradoxical potential to both abrogate as well as exacerbate asthma; and (5) endotoxin's role as a marker for other similar pathogen-associated molecular patterns." @default.
- W2061058105 created "2016-06-24" @default.
- W2061058105 creator A5002650446 @default.
- W2061058105 creator A5031723806 @default.
- W2061058105 date "2003-10-01" @default.
- W2061058105 modified "2023-09-24" @default.
- W2061058105 title "Metropolitan endotoxin exposure, allergy and asthma" @default.
- W2061058105 cites W1514540900 @default.
- W2061058105 cites W1526590732 @default.
- W2061058105 cites W1971385626 @default.
- W2061058105 cites W1979023453 @default.
- W2061058105 cites W1981190604 @default.
- W2061058105 cites W1981614300 @default.
- W2061058105 cites W1985478099 @default.
- W2061058105 cites W1993554645 @default.
- W2061058105 cites W1993731281 @default.
- W2061058105 cites W2004773897 @default.
- W2061058105 cites W2007161982 @default.
- W2061058105 cites W2008877685 @default.
- W2061058105 cites W2009727104 @default.
- W2061058105 cites W2011659244 @default.
- W2061058105 cites W2019343358 @default.
- W2061058105 cites W2028196782 @default.
- W2061058105 cites W2030979378 @default.
- W2061058105 cites W2044482869 @default.
- W2061058105 cites W2044763085 @default.
- W2061058105 cites W2060483497 @default.
- W2061058105 cites W2065910611 @default.
- W2061058105 cites W2066718029 @default.
- W2061058105 cites W2070479807 @default.
- W2061058105 cites W2073745943 @default.
- W2061058105 cites W2075361349 @default.
- W2061058105 cites W2078142776 @default.
- W2061058105 cites W2082319236 @default.
- W2061058105 cites W2114039247 @default.
- W2061058105 cites W2116029913 @default.
- W2061058105 cites W2118011548 @default.
- W2061058105 cites W2123636816 @default.
- W2061058105 cites W2131861902 @default.
- W2061058105 cites W2134204376 @default.
- W2061058105 cites W2140862987 @default.
- W2061058105 cites W2146700420 @default.
- W2061058105 cites W2158567910 @default.
- W2061058105 cites W2161853794 @default.
- W2061058105 cites W2170465378 @default.
- W2061058105 doi "https://doi.org/10.1097/00130832-200310000-00002" @default.
- W2061058105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14501430" @default.
- W2061058105 hasPublicationYear "2003" @default.
- W2061058105 type Work @default.
- W2061058105 sameAs 2061058105 @default.
- W2061058105 citedByCount "12" @default.
- W2061058105 countsByYear W20610581052018 @default.
- W2061058105 crossrefType "journal-article" @default.
- W2061058105 hasAuthorship W2061058105A5002650446 @default.
- W2061058105 hasAuthorship W2061058105A5031723806 @default.
- W2061058105 hasConcept C126322002 @default.
- W2061058105 hasConcept C203014093 @default.
- W2061058105 hasConcept C207480886 @default.
- W2061058105 hasConcept C2776042228 @default.
- W2061058105 hasConcept C2776217527 @default.
- W2061058105 hasConcept C2777697326 @default.
- W2061058105 hasConcept C2779134260 @default.
- W2061058105 hasConcept C71924100 @default.
- W2061058105 hasConcept C78635009 @default.
- W2061058105 hasConcept C8891405 @default.
- W2061058105 hasConceptScore W2061058105C126322002 @default.
- W2061058105 hasConceptScore W2061058105C203014093 @default.
- W2061058105 hasConceptScore W2061058105C207480886 @default.
- W2061058105 hasConceptScore W2061058105C2776042228 @default.
- W2061058105 hasConceptScore W2061058105C2776217527 @default.
- W2061058105 hasConceptScore W2061058105C2777697326 @default.
- W2061058105 hasConceptScore W2061058105C2779134260 @default.
- W2061058105 hasConceptScore W2061058105C71924100 @default.
- W2061058105 hasConceptScore W2061058105C78635009 @default.
- W2061058105 hasConceptScore W2061058105C8891405 @default.
- W2061058105 hasIssue "5" @default.
- W2061058105 hasLocation W20610581051 @default.
- W2061058105 hasLocation W20610581052 @default.
- W2061058105 hasOpenAccess W2061058105 @default.
- W2061058105 hasPrimaryLocation W20610581051 @default.
- W2061058105 hasRelatedWork W1498269385 @default.
- W2061058105 hasRelatedWork W1955056040 @default.
- W2061058105 hasRelatedWork W1992095531 @default.
- W2061058105 hasRelatedWork W1992480592 @default.
- W2061058105 hasRelatedWork W2008857105 @default.
- W2061058105 hasRelatedWork W2051578708 @default.
- W2061058105 hasRelatedWork W2061477629 @default.
- W2061058105 hasRelatedWork W2063730174 @default.
- W2061058105 hasRelatedWork W2145829877 @default.
- W2061058105 hasRelatedWork W2154337427 @default.
- W2061058105 hasVolume "3" @default.
- W2061058105 isParatext "false" @default.
- W2061058105 isRetracted "false" @default.
- W2061058105 magId "2061058105" @default.
- W2061058105 workType "article" @default.