FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061058995> ?p ?o ?g. }

• W2061058995 endingPage "3856" @default.
• W2061058995 startingPage "3850" @default.
• W2061058995 abstract "A rapid liquid chromatography/positive ion electrospray mass spectrometric assay (LC/ESI-MS) was developed for the quantitation of methotrexate, folinic acid, folic acid and ondansetron in human serum. The assay was based on 100 μL serum samples, following acetonitrile precipitation of proteins and filtration that enabled direct injection into the LC/MS system. All analytes and the internal standard, alfuzosin, were separated by using a Zorbax Eclipse XDB–C8 analytical column (2.1 mm × 150.0 mm i.d., particle size 3.5 μm) with isocratic elution. The mobile phase was composed of a mixture of water/acetonitrile containing 0.1%, v/v formic acid (75:25, v/v), pumped at a flow rate of 0.15 mL min−1. Quantitation of the analytes was performed with selected ion monitoring (SIM) in positive ionization mode using electrospray ionization interface. The assay was found to be linear in the concentration range of 0.01–25.00 μg mL−1 for methotrexate and 0.01–5.00 μg mL−1 for folic acid, folinic acid and ondansetron. Intermediate precision was found to be less than 4.2% over the tested concentration ranges. A run time of less than 7.0 min for each sample made it possible to analyze a large number of human serum samples per day. The method can be used to quantify methotrexate, folinic acid, folic acid and ondansetron in human serum covering a variety of clinical studies and it was applied to the analysis of human serum samples obtained from children with acute lymphoblastic leukemia." @default.
• W2061058995 created "2016-06-24" @default.
• W2061058995 creator A5003692560 @default.
• W2061058995 creator A5023039928 @default.
• W2061058995 creator A5024893785 @default.
• W2061058995 creator A5038367562 @default.
• W2061058995 creator A5055100744 @default.
• W2061058995 creator A5074459352 @default.
• W2061058995 creator A5089626922 @default.
• W2061058995 date "2009-11-01" @default.
• W2061058995 modified "2023-10-09" @default.
• W2061058995 title "Direct injection liquid chromatography/positive ion electrospray ionization mass spectrometric quantification of methotrexate, folinic acid, folic acid and ondansetron in human serum" @default.
• W2061058995 cites W1970522999 @default.
• W2061058995 cites W1976465869 @default.
• W2061058995 cites W1982585544 @default.
• W2061058995 cites W1993134215 @default.
• W2061058995 cites W1995925329 @default.
• W2061058995 cites W2000542203 @default.
• W2061058995 cites W2003392697 @default.
• W2061058995 cites W2007124805 @default.
• W2061058995 cites W2013623834 @default.
• W2061058995 cites W2019981267 @default.
• W2061058995 cites W2023361859 @default.
• W2061058995 cites W2024926557 @default.
• W2061058995 cites W2025203456 @default.
• W2061058995 cites W2028015236 @default.
• W2061058995 cites W2028766089 @default.
• W2061058995 cites W2035684949 @default.
• W2061058995 cites W2039247721 @default.
• W2061058995 cites W2040463362 @default.
• W2061058995 cites W2044193540 @default.
• W2061058995 cites W2050226999 @default.
• W2061058995 cites W2051242623 @default.
• W2061058995 cites W2051340033 @default.
• W2061058995 cites W2062261210 @default.
• W2061058995 cites W2066591623 @default.
• W2061058995 cites W2067428649 @default.
• W2061058995 cites W2068429678 @default.
• W2061058995 cites W2070563794 @default.
• W2061058995 cites W2075248375 @default.
• W2061058995 cites W2077440173 @default.
• W2061058995 cites W2118937700 @default.
• W2061058995 cites W2130705999 @default.
• W2061058995 cites W2153596481 @default.
• W2061058995 cites W2164959344 @default.
• W2061058995 cites W1919736612 @default.
• W2061058995 doi "https://doi.org/10.1016/j.jchromb.2009.09.034" @default.
• W2061058995 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19828383" @default.
• W2061058995 hasPublicationYear "2009" @default.
• W2061058995 type Work @default.
• W2061058995 sameAs 2061058995 @default.
• W2061058995 citedByCount "43" @default.
• W2061058995 countsByYear W20610589952012 @default.
• W2061058995 countsByYear W20610589952013 @default.
• W2061058995 countsByYear W20610589952014 @default.
• W2061058995 countsByYear W20610589952015 @default.
• W2061058995 countsByYear W20610589952016 @default.
• W2061058995 countsByYear W20610589952017 @default.
• W2061058995 countsByYear W20610589952018 @default.
• W2061058995 countsByYear W20610589952020 @default.
• W2061058995 countsByYear W20610589952023 @default.
• W2061058995 crossrefType "journal-article" @default.
• W2061058995 hasAuthorship W2061058995A5003692560 @default.
• W2061058995 hasAuthorship W2061058995A5023039928 @default.
• W2061058995 hasAuthorship W2061058995A5024893785 @default.
• W2061058995 hasAuthorship W2061058995A5038367562 @default.
• W2061058995 hasAuthorship W2061058995A5055100744 @default.
• W2061058995 hasAuthorship W2061058995A5074459352 @default.
• W2061058995 hasAuthorship W2061058995A5089626922 @default.
• W2061058995 hasConcept C119128265 @default.
• W2061058995 hasConcept C121608353 @default.
• W2061058995 hasConcept C126322002 @default.
• W2061058995 hasConcept C162356407 @default.
• W2061058995 hasConcept C185592680 @default.
• W2061058995 hasConcept C2777379063 @default.
• W2061058995 hasConcept C2779804826 @default.
• W2061058995 hasConcept C40684141 @default.
• W2061058995 hasConcept C43617362 @default.
• W2061058995 hasConcept C526805850 @default.
• W2061058995 hasConcept C71924100 @default.
• W2061058995 hasConcept C74774607 @default.
• W2061058995 hasConceptScore W2061058995C119128265 @default.
• W2061058995 hasConceptScore W2061058995C121608353 @default.
• W2061058995 hasConceptScore W2061058995C126322002 @default.
• W2061058995 hasConceptScore W2061058995C162356407 @default.
• W2061058995 hasConceptScore W2061058995C185592680 @default.
• W2061058995 hasConceptScore W2061058995C2777379063 @default.
• W2061058995 hasConceptScore W2061058995C2779804826 @default.
• W2061058995 hasConceptScore W2061058995C40684141 @default.
• W2061058995 hasConceptScore W2061058995C43617362 @default.
• W2061058995 hasConceptScore W2061058995C526805850 @default.
• W2061058995 hasConceptScore W2061058995C71924100 @default.
• W2061058995 hasConceptScore W2061058995C74774607 @default.
• W2061058995 hasIssue "30" @default.
• W2061058995 hasLocation W20610589951 @default.
• W2061058995 hasLocation W20610589952 @default.
• W2061058995 hasOpenAccess W2061058995 @default.
• W2061058995 hasPrimaryLocation W20610589951 @default.

• next