Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061065493> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2061065493 abstract "The intermediate filament, glial fibrillary acidic protein (GFAP) has proven to be an important glial marker in diagnostic neuropathology. We report the histochemical application of three monoclonal antibodies (Mab) produced in this laboratory, 1B4, 2E1, and 4A11, which are monospecific to GFAP by radioimmunoassay, immunoblot electrophoresis, and immunoperoxidase histochemistry. The goal of this study was to compare the specificity and sensitivity of these Mab to GFAP on surgical brain biopsy specimens which had been routinely processed for diagnostic neuropathology with that of a high titer, highly specific, reference polyvalent anti-GFAP antiserum. The Mab stained astrocytes specifically in normal brain. When combined in a cocktail preparation, the quality of the immunoperoxidase detection of GFAP by these Mab closely approached that of the reference serum in 71 intracranial and intraspinal neoplasms. As these three Mab represent a continuous supply of a well defined, monospecific reagent, the monoclonal cocktail represents a standard reagent for large multi-institutional studies and for studies extending over a period of time." @default.
- W2061065493 created "2016-06-24" @default.
- W2061065493 creator A5004814459 @default.
- W2061065493 creator A5008607260 @default.
- W2061065493 creator A5026609192 @default.
- W2061065493 creator A5055182800 @default.
- W2061065493 creator A5073862375 @default.
- W2061065493 date "1986-11-01" @default.
- W2061065493 modified "2023-10-16" @default.
- W2061065493 title "The Immunohistochemical Application of Three Anti-GFAP Monoclonal Antibodies to Formalin-fixed, Paraffin-embedded, Normal and Neoplastic Brain Tissues" @default.
- W2061065493 doi "https://doi.org/10.1097/00005072-198611000-00007" @default.
- W2061065493 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3534145" @default.
- W2061065493 hasPublicationYear "1986" @default.
- W2061065493 type Work @default.
- W2061065493 sameAs 2061065493 @default.
- W2061065493 citedByCount "40" @default.
- W2061065493 countsByYear W20610654932012 @default.
- W2061065493 countsByYear W20610654932015 @default.
- W2061065493 countsByYear W20610654932016 @default.
- W2061065493 countsByYear W20610654932017 @default.
- W2061065493 countsByYear W20610654932019 @default.
- W2061065493 crossrefType "journal-article" @default.
- W2061065493 hasAuthorship W2061065493A5004814459 @default.
- W2061065493 hasAuthorship W2061065493A5008607260 @default.
- W2061065493 hasAuthorship W2061065493A5026609192 @default.
- W2061065493 hasAuthorship W2061065493A5055182800 @default.
- W2061065493 hasAuthorship W2061065493A5073862375 @default.
- W2061065493 hasBestOaLocation W20610654931 @default.
- W2061065493 hasConcept C128102431 @default.
- W2061065493 hasConcept C142724271 @default.
- W2061065493 hasConcept C153911025 @default.
- W2061065493 hasConcept C157207234 @default.
- W2061065493 hasConcept C159431405 @default.
- W2061065493 hasConcept C159654299 @default.
- W2061065493 hasConcept C163864487 @default.
- W2061065493 hasConcept C203014093 @default.
- W2061065493 hasConcept C204232928 @default.
- W2061065493 hasConcept C2779134260 @default.
- W2061065493 hasConcept C2780130745 @default.
- W2061065493 hasConcept C2780495277 @default.
- W2061065493 hasConcept C542903549 @default.
- W2061065493 hasConcept C71924100 @default.
- W2061065493 hasConcept C86803240 @default.
- W2061065493 hasConcept C91523082 @default.
- W2061065493 hasConceptScore W2061065493C128102431 @default.
- W2061065493 hasConceptScore W2061065493C142724271 @default.
- W2061065493 hasConceptScore W2061065493C153911025 @default.
- W2061065493 hasConceptScore W2061065493C157207234 @default.
- W2061065493 hasConceptScore W2061065493C159431405 @default.
- W2061065493 hasConceptScore W2061065493C159654299 @default.
- W2061065493 hasConceptScore W2061065493C163864487 @default.
- W2061065493 hasConceptScore W2061065493C203014093 @default.
- W2061065493 hasConceptScore W2061065493C204232928 @default.
- W2061065493 hasConceptScore W2061065493C2779134260 @default.
- W2061065493 hasConceptScore W2061065493C2780130745 @default.
- W2061065493 hasConceptScore W2061065493C2780495277 @default.
- W2061065493 hasConceptScore W2061065493C542903549 @default.
- W2061065493 hasConceptScore W2061065493C71924100 @default.
- W2061065493 hasConceptScore W2061065493C86803240 @default.
- W2061065493 hasConceptScore W2061065493C91523082 @default.
- W2061065493 hasLocation W20610654931 @default.
- W2061065493 hasLocation W20610654932 @default.
- W2061065493 hasOpenAccess W2061065493 @default.
- W2061065493 hasPrimaryLocation W20610654931 @default.
- W2061065493 hasRelatedWork W1978777644 @default.
- W2061065493 hasRelatedWork W1988417143 @default.
- W2061065493 hasRelatedWork W2033675264 @default.
- W2061065493 hasRelatedWork W2043797153 @default.
- W2061065493 hasRelatedWork W2061065493 @default.
- W2061065493 hasRelatedWork W2100623527 @default.
- W2061065493 hasRelatedWork W2398595763 @default.
- W2061065493 hasRelatedWork W2416375204 @default.
- W2061065493 hasRelatedWork W2475249793 @default.
- W2061065493 hasRelatedWork W2502917570 @default.
- W2061065493 isParatext "false" @default.
- W2061065493 isRetracted "false" @default.
- W2061065493 magId "2061065493" @default.
- W2061065493 workType "article" @default.