FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061067314> ?p ?o ?g. }

• W2061067314 endingPage "1386" @default.
• W2061067314 startingPage "1380" @default.
• W2061067314 abstract "Abstract: Cellular energetic parameters including the intramitochondrial and cytosolic [NAD+]/[NADH] ratios, the cellular [ATP]/[ADP][Pi and [creatine phosphate]/[creatine] ratios, the concentration of cytochrome c and its redox state and the respiratory rate were studied in suspensions of rat brain synapto-somes isolated from nembutal-anesthetized and nonanesthetized animals. The ratio of [3-hydroxybutyrate] to [acetoacetate] was 2.0 in synaptosomes isolated from nonanesthetized rats and 5.55 in those from anesthetized animals. The [lactate]/[pyruvate] ratio was 3.8 in the former and 10.9 in the latter preparation. The [ATP]/[ADP][Pi] was 3838 M−1 in the synaptosomes from anesthetized rats and 840 M−1 in those from nonanesthetized animals and the [creatine phosphate]/[creatine] ratios were 0.79 and 0.39, respectively. Cytochrome c was about 15% reduced in both preparations; however, the mitochon-drial cytochrome concentration was almost twofold higher in the synaptosomes from nonanesthetized animals. Calculations of the free energy relationships between the mitochondrial redox reactions and ATP synthesis showed that in synaptosomes isolated from the brains of nembutal-anesthetized rats the first two sites of oxidative phosphorylation were at near-equilibrium, in agreement with observations for intact cells and tissues. The energetic parameters for synaptosomes from anesthetized rats are very similar to the values for intact whole brain, whereas those for synaptosomes from nonanesthetized rats are lower and suggest that nembutal anesthesia protects against some irreversible damage to the synaptosome during isolation. It is concluded that synaptosomes isolated from brains of nembutal-anesthetized rats can be used as a convenient model system for studies of neuronal metabolism." @default.
• W2061067314 created "2016-06-24" @default.
• W2061067314 creator A5067296563 @default.
• W2061067314 creator A5079229712 @default.
• W2061067314 creator A5091130384 @default.
• W2061067314 date "1980-06-01" @default.
• W2061067314 modified "2023-09-26" @default.
• W2061067314 title "Energy Metabolism in Rat Brain Synaptosomes from Nembutal-Anesthetized and Nonanesthetized Animals" @default.
• W2061067314 cites W1489218150 @default.
• W2061067314 cites W1546087498 @default.
• W2061067314 cites W1554211606 @default.
• W2061067314 cites W1684534765 @default.
• W2061067314 cites W170425602 @default.
• W2061067314 cites W1775749144 @default.
• W2061067314 cites W1801184284 @default.
• W2061067314 cites W1979596483 @default.
• W2061067314 cites W2008353297 @default.
• W2061067314 cites W2022689287 @default.
• W2061067314 cites W2028089537 @default.
• W2061067314 cites W2036754828 @default.
• W2061067314 cites W2041003109 @default.
• W2061067314 cites W2043231803 @default.
• W2061067314 cites W2049868269 @default.
• W2061067314 cites W2067753855 @default.
• W2061067314 cites W2074706094 @default.
• W2061067314 cites W2084477404 @default.
• W2061067314 cites W2085836913 @default.
• W2061067314 cites W2093804401 @default.
• W2061067314 cites W2131182702 @default.
• W2061067314 cites W2146250938 @default.
• W2061067314 cites W2157853787 @default.
• W2061067314 cites W2176224597 @default.
• W2061067314 cites W2223201108 @default.
• W2061067314 cites W2230785117 @default.
• W2061067314 cites W2250961987 @default.
• W2061067314 cites W2407904205 @default.
• W2061067314 cites W2471261377 @default.
• W2061067314 cites W4238488379 @default.
• W2061067314 cites W4245195685 @default.
• W2061067314 cites W4255185016 @default.
• W2061067314 cites W62898540 @default.
• W2061067314 cites W981847729 @default.
• W2061067314 doi "https://doi.org/10.1111/j.1471-4159.1980.tb11218.x" @default.
• W2061067314 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6247445" @default.
• W2061067314 hasPublicationYear "1980" @default.
• W2061067314 type Work @default.
• W2061067314 sameAs 2061067314 @default.
• W2061067314 citedByCount "64" @default.
• W2061067314 countsByYear W20610673142012 @default.
• W2061067314 crossrefType "journal-article" @default.
• W2061067314 hasAuthorship W2061067314A5067296563 @default.
• W2061067314 hasAuthorship W2061067314A5079229712 @default.
• W2061067314 hasAuthorship W2061067314A5091130384 @default.
• W2061067314 hasConcept C105702510 @default.
• W2061067314 hasConcept C126322002 @default.
• W2061067314 hasConcept C134018914 @default.
• W2061067314 hasConcept C178790620 @default.
• W2061067314 hasConcept C181199279 @default.
• W2061067314 hasConcept C182215343 @default.
• W2061067314 hasConcept C185592680 @default.
• W2061067314 hasConcept C2776932660 @default.
• W2061067314 hasConcept C2778921374 @default.
• W2061067314 hasConcept C2779896295 @default.
• W2061067314 hasConcept C2780768313 @default.
• W2061067314 hasConcept C28859421 @default.
• W2061067314 hasConcept C41625074 @default.
• W2061067314 hasConcept C55493867 @default.
• W2061067314 hasConcept C57600042 @default.
• W2061067314 hasConcept C62231903 @default.
• W2061067314 hasConcept C71924100 @default.
• W2061067314 hasConcept C86803240 @default.
• W2061067314 hasConcept C98274493 @default.
• W2061067314 hasConceptScore W2061067314C105702510 @default.
• W2061067314 hasConceptScore W2061067314C126322002 @default.
• W2061067314 hasConceptScore W2061067314C134018914 @default.
• W2061067314 hasConceptScore W2061067314C178790620 @default.
• W2061067314 hasConceptScore W2061067314C181199279 @default.
• W2061067314 hasConceptScore W2061067314C182215343 @default.
• W2061067314 hasConceptScore W2061067314C185592680 @default.
• W2061067314 hasConceptScore W2061067314C2776932660 @default.
• W2061067314 hasConceptScore W2061067314C2778921374 @default.
• W2061067314 hasConceptScore W2061067314C2779896295 @default.
• W2061067314 hasConceptScore W2061067314C2780768313 @default.
• W2061067314 hasConceptScore W2061067314C28859421 @default.
• W2061067314 hasConceptScore W2061067314C41625074 @default.
• W2061067314 hasConceptScore W2061067314C55493867 @default.
• W2061067314 hasConceptScore W2061067314C57600042 @default.
• W2061067314 hasConceptScore W2061067314C62231903 @default.
• W2061067314 hasConceptScore W2061067314C71924100 @default.
• W2061067314 hasConceptScore W2061067314C86803240 @default.
• W2061067314 hasConceptScore W2061067314C98274493 @default.
• W2061067314 hasIssue "6" @default.
• W2061067314 hasLocation W20610673141 @default.
• W2061067314 hasLocation W20610673142 @default.
• W2061067314 hasOpenAccess W2061067314 @default.
• W2061067314 hasPrimaryLocation W20610673141 @default.
• W2061067314 hasRelatedWork W1980986648 @default.
• W2061067314 hasRelatedWork W2041949500 @default.

• next