Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061158041> ?p ?o ?g. }
- W2061158041 endingPage "647" @default.
- W2061158041 startingPage "637" @default.
- W2061158041 abstract "Solubilization capacity and structural transformations in nonionic microemulsions characterized by a large continuous isotropic region forming dilutable self-assembled nanodroplets containing solubilized carbamazepine, were studied along dilution lines 73 and 82 (70 and 80 wt% surfactant and 30 and 20 wt% of oil phase, respectively). The preparations were based on pharma-grade ingredients, water, R-(+)-limonene, ethanol, propylene glycol, and Tween 60. Solubilization capacity (SC) of the drug was dependent on the microstructure of the microemulsion and on the surfactant-to-oil phase weight ratio. The SC in the concentrate (reversed micelles) was 15 times higher than its solubility in the oil. Transition of the W/O microemulsion to a bicontinuous phase and to O/W droplets were indentified by electrical conductivity, viscosity, SAXS, and SD-NMR measurements. Once the system is diluted to 90 wt% aqueous phase, the SC is 10 and 16-fold higher, along dilution lines 73 and 82, respectively, than in pure water. Being solubilized, carbamazepine serves as a cosurfactant therefore it affects the curvatures of the microstructures and consequently the boundaries of the structural regions and the transition points between the different phases. Dilutable microemulsions are promising new carbamazepine vehicles for oral intake." @default.
- W2061158041 created "2016-06-24" @default.
- W2061158041 creator A5003332003 @default.
- W2061158041 creator A5024670229 @default.
- W2061158041 creator A5075667964 @default.
- W2061158041 date "2007-11-01" @default.
- W2061158041 modified "2023-09-23" @default.
- W2061158041 title "Improved solubilization of carbamazepine and structural transitions in nonionic microemulsions upon aqueous phase dilution" @default.
- W2061158041 cites W117515709 @default.
- W2061158041 cites W1204935804 @default.
- W2061158041 cites W1513071117 @default.
- W2061158041 cites W1964779269 @default.
- W2061158041 cites W1967314916 @default.
- W2061158041 cites W1969264165 @default.
- W2061158041 cites W1970353605 @default.
- W2061158041 cites W1975882538 @default.
- W2061158041 cites W1979411772 @default.
- W2061158041 cites W1982285805 @default.
- W2061158041 cites W1982301999 @default.
- W2061158041 cites W1982677101 @default.
- W2061158041 cites W1984196661 @default.
- W2061158041 cites W1986638516 @default.
- W2061158041 cites W1991186657 @default.
- W2061158041 cites W1991616806 @default.
- W2061158041 cites W1997515328 @default.
- W2061158041 cites W1997742741 @default.
- W2061158041 cites W2000966264 @default.
- W2061158041 cites W2007754754 @default.
- W2061158041 cites W2012090511 @default.
- W2061158041 cites W2021205408 @default.
- W2061158041 cites W2027092795 @default.
- W2061158041 cites W2029574334 @default.
- W2061158041 cites W2029833430 @default.
- W2061158041 cites W2033604843 @default.
- W2061158041 cites W2036892245 @default.
- W2061158041 cites W2038452671 @default.
- W2061158041 cites W2038471903 @default.
- W2061158041 cites W2039096198 @default.
- W2061158041 cites W2046190665 @default.
- W2061158041 cites W2048967679 @default.
- W2061158041 cites W2052920306 @default.
- W2061158041 cites W2055896137 @default.
- W2061158041 cites W2057990963 @default.
- W2061158041 cites W2070033953 @default.
- W2061158041 cites W2072374838 @default.
- W2061158041 cites W2072944515 @default.
- W2061158041 cites W2073029697 @default.
- W2061158041 cites W2082735927 @default.
- W2061158041 cites W2086806090 @default.
- W2061158041 cites W2086850403 @default.
- W2061158041 cites W2117137169 @default.
- W2061158041 cites W2122650338 @default.
- W2061158041 cites W2126810667 @default.
- W2061158041 cites W2139887680 @default.
- W2061158041 cites W91604478 @default.
- W2061158041 doi "https://doi.org/10.1016/j.jcis.2007.06.087" @default.
- W2061158041 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17825310" @default.
- W2061158041 hasPublicationYear "2007" @default.
- W2061158041 type Work @default.
- W2061158041 sameAs 2061158041 @default.
- W2061158041 citedByCount "62" @default.
- W2061158041 countsByYear W20611580412012 @default.
- W2061158041 countsByYear W20611580412013 @default.
- W2061158041 countsByYear W20611580412014 @default.
- W2061158041 countsByYear W20611580412015 @default.
- W2061158041 countsByYear W20611580412016 @default.
- W2061158041 countsByYear W20611580412017 @default.
- W2061158041 countsByYear W20611580412018 @default.
- W2061158041 countsByYear W20611580412019 @default.
- W2061158041 countsByYear W20611580412020 @default.
- W2061158041 countsByYear W20611580412021 @default.
- W2061158041 crossrefType "journal-article" @default.
- W2061158041 hasAuthorship W2061158041A5003332003 @default.
- W2061158041 hasAuthorship W2061158041A5024670229 @default.
- W2061158041 hasAuthorship W2061158041A5075667964 @default.
- W2061158041 hasConcept C11268172 @default.
- W2061158041 hasConcept C121332964 @default.
- W2061158041 hasConcept C127413603 @default.
- W2061158041 hasConcept C149556010 @default.
- W2061158041 hasConcept C155574463 @default.
- W2061158041 hasConcept C178790620 @default.
- W2061158041 hasConcept C184651966 @default.
- W2061158041 hasConcept C185592680 @default.
- W2061158041 hasConcept C190119865 @default.
- W2061158041 hasConcept C2779716929 @default.
- W2061158041 hasConcept C42360764 @default.
- W2061158041 hasConcept C43617362 @default.
- W2061158041 hasConcept C44280652 @default.
- W2061158041 hasConcept C55493867 @default.
- W2061158041 hasConcept C58226133 @default.
- W2061158041 hasConcept C96618451 @default.
- W2061158041 hasConcept C97355855 @default.
- W2061158041 hasConceptScore W2061158041C11268172 @default.
- W2061158041 hasConceptScore W2061158041C121332964 @default.
- W2061158041 hasConceptScore W2061158041C127413603 @default.
- W2061158041 hasConceptScore W2061158041C149556010 @default.
- W2061158041 hasConceptScore W2061158041C155574463 @default.
- W2061158041 hasConceptScore W2061158041C178790620 @default.