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• W2061195400 abstract "Abstract Diets containing deoxynivalenol ( DON ) were fed to rainbow trout O ncorhynchus mykiss (Walbaum) for 4 weeks followed by experimental infection (intraperitoneal) with F lavobacterium psychrophilum (4.1 × 10 6 colony‐forming units [ CFU ] mL −1 ). Mortality of rainbow trout fed either 6.4 mg kg −1 DON or trout pair‐fed the control diet was significantly reduced ( P < 0.05) in comparison with trout fed the control diet to apparent satiation (<0.1 mg kg −1 DON ). In a second experiment, trout were fed one of three experimental diets; a control diet, a diet produced with corn naturally contaminated with DON (3.3 mg kg −1 DON ) or a diet containing purified DON (3.8 mg kg −1 ); however, these fish were not experimentally infected. The presence of DON resulted in significant reduction ( P < 0.0001) in feed intake as well as weight gain after 4 weeks. Respiratory burst of head‐kidney leucocytes isolated from rainbow trout fed diets containing purified DON (3.8 mg kg −1 ) was significantly higher ( P < 0.05) at 35 day post‐exposure compared with controls. The antimicrobial activity of DON was examined by subjecting F. psychrophilum in vitro to serial dilutions of the chemical. Complete inhibition occurred at a concentration of 75 mg L −1 DON , but no effect was observed below this concentration (0–30 mg L −1 )." @default.
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• W2061195400 date "2014-08-27" @default.
• W2061195400 modified "2023-10-03" @default.
• W2061195400 title "Purified deoxynivalenol or feed restriction reduces mortality in rainbow trout, Oncorhynchus mykiss (Walbaum), with experimental bacterial coldwater disease but biologically relevant concentrations of deoxynivalenol do not impair the growth of Flavobacter" @default.
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• W2061195400 doi "https://doi.org/10.1111/jfd.12295" @default.
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