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• W2061224018 abstract "Abstract Background The aim of this study was to investigate the effects of D2 lymphadenectomy with spleen preservation on surgical outcomes in locally advanced proximal gastric cancer. Methods Between January 2000 and December 2004, a total of 366 patients who underwent curative total gastrectomy were studied retrospectively from a prospectively designed database. Results The spleen‐preservation group experienced shorter operation times, a lower incidence of perioperative transfusion, and shorter postoperative hospital stays. Perioperative transfusion and splenectomy were independent risk factors for morbidity. There was no significant difference between the two groups in recurrence or cumulative survival rate when adjusted according to cancer stage. Multivariate analysis showed that tumor size, serosal invasion, and nodal metastasis were independent prognostic factors, while splenectomy was not. The cumulative survival rate in pN0‐status patients was significantly higher in the spleen‐preservation group, while there was no significant difference in the survival of pN1‐ or pN2‐status patients between the two groups. Conclusions Splenectomy for lymph node dissection in proximal gastric cancer patients obviously showed poor short‐surgical outcomes, but it did not affect long‐term outcomes in terms of recurrence and overall survival rate. Therefore, spleen‐preserving lymphadenectomy is a feasible method for radical surgery in locally advanced proximal gastric cancer. J. Surg. Oncol. 2009;99:275–280. © 2009 Wiley‐Liss, Inc." @default.
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• W2061224018 date "2009-03-17" @default.
• W2061224018 modified "2023-10-09" @default.
• W2061224018 title "The effect of spleen-preserving lymphadenectomy on surgical outcomes of locally advanced proximal gastric cancer" @default.
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• W2061224018 doi "https://doi.org/10.1002/jso.21229" @default.
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