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- W2061241903 abstract "We have used particle induced X-ray emission (PIXE) to analyze the elemental compositions and uptakes of a lanthanide, yttrium in this report, in tumors and normal tissues of nude mice. A small amount of yttrium nitrate was injected into nude mice with tumors. Samples of normal and malignant tissues taken from these mice were bombarded by the 2 MeV proton beam from a 3 MeV Van de Graaff accelerator with a Ge detector system to determine the relative elemental compositions of tissues and the relative concentrations of yttrium taken up by these tissues. We found that the uptakes of yttrium by tumors were at least five times more than those by normal tissues. Substantial differences were often observed between the trace element weight (or concentration) pattern of the cancerous and normal tissues. The present result is compared with human tissues." @default.
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- W2061241903 date "1984-04-01" @default.
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- W2061241903 title "PIXE analysis of tumors and localization behavior of a lanthanide in nude mice" @default.
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- W2061241903 doi "https://doi.org/10.1016/0168-583x(84)90402-6" @default.
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