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- W2061320431 abstract "Mitochondria are cellular organelles that are required for energy production. Emerging evidence demonstrates their role in oocyte development and reproduction. In this review, we examine recent animal and clinical studies on the role of mitochondria in fertility. We also analyse the impact of assisted reproductive techniques (ARTs) on mitochondrial function and discuss the future clinical implications of mitochondrial nutrients and mitochondrial replacement.Mitochondria affect all aspects of mammalian reproduction. They are essential for optimal oocyte maturation, fertilization and embryonic development. Mitochondrial dysfunction causes a decrease in oocyte quality and interferes with embryonic development. ART procedures affect mitochondrial function, while mitochondrial nutrients may increase mitochondrial performance in oocytes. New mitochondrial replacement procedures using mitochondria obtained from polar bodies or from the patient's own oogonial stem cells are promising and may address concerns related to the induction of high-levels of heteroplasmy, which could potentially result in negative long-term health effects.Optimal energy production is required for oocyte and embryo development, and mitochondrial abnormalities have devastating reproductive consequences. Improvement of oocyte mitochondrial function via intake of compounds that boost mitochondrial activity may have clinical benefits, and mitochondrial replacement could potentially be used for the prevention of mitochondrial diseases." @default.
- W2061320431 created "2016-06-24" @default.
- W2061320431 creator A5079490860 @default.
- W2061320431 creator A5082020231 @default.
- W2061320431 date "2015-06-01" @default.
- W2061320431 modified "2023-10-04" @default.
- W2061320431 title "Oocyte mitochondrial function and reproduction" @default.
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- W2061320431 cites W1966044281 @default.
- W2061320431 cites W1966649193 @default.
- W2061320431 cites W1967058526 @default.
- W2061320431 cites W1968408636 @default.
- W2061320431 cites W1968471129 @default.
- W2061320431 cites W1968879203 @default.
- W2061320431 cites W1975223491 @default.
- W2061320431 cites W1976069063 @default.
- W2061320431 cites W1978691222 @default.
- W2061320431 cites W1979783538 @default.
- W2061320431 cites W1980642844 @default.
- W2061320431 cites W1981640446 @default.
- W2061320431 cites W1982103775 @default.
- W2061320431 cites W1982858056 @default.
- W2061320431 cites W1986665847 @default.
- W2061320431 cites W1986945602 @default.
- W2061320431 cites W1988876420 @default.
- W2061320431 cites W1989180582 @default.
- W2061320431 cites W1990527421 @default.
- W2061320431 cites W1994873102 @default.
- W2061320431 cites W1996943057 @default.
- W2061320431 cites W2000454435 @default.
- W2061320431 cites W2004516831 @default.
- W2061320431 cites W2010689400 @default.
- W2061320431 cites W2011116207 @default.
- W2061320431 cites W2011813182 @default.
- W2061320431 cites W2019856376 @default.
- W2061320431 cites W2020127384 @default.
- W2061320431 cites W2021957622 @default.
- W2061320431 cites W2029716263 @default.
- W2061320431 cites W2040151712 @default.
- W2061320431 cites W2044897807 @default.
- W2061320431 cites W2050183773 @default.
- W2061320431 cites W2050851353 @default.
- W2061320431 cites W2053335209 @default.
- W2061320431 cites W2053829558 @default.
- W2061320431 cites W2053901293 @default.
- W2061320431 cites W2055360428 @default.
- W2061320431 cites W2058707355 @default.
- W2061320431 cites W2061167268 @default.
- W2061320431 cites W2062906638 @default.
- W2061320431 cites W2066193715 @default.
- W2061320431 cites W2070392246 @default.
- W2061320431 cites W2071337010 @default.
- W2061320431 cites W2071592190 @default.
- W2061320431 cites W2074261055 @default.
- W2061320431 cites W2075204347 @default.
- W2061320431 cites W2077860881 @default.
- W2061320431 cites W2098405795 @default.
- W2061320431 cites W2100844417 @default.
- W2061320431 cites W2101234364 @default.
- W2061320431 cites W2101472329 @default.
- W2061320431 cites W2104658942 @default.
- W2061320431 cites W2105784380 @default.
- W2061320431 cites W2111821999 @default.
- W2061320431 cites W2113729748 @default.
- W2061320431 cites W2116192451 @default.
- W2061320431 cites W2122073743 @default.
- W2061320431 cites W2124128749 @default.
- W2061320431 cites W2124855292 @default.
- W2061320431 cites W2128504154 @default.
- W2061320431 cites W2129028562 @default.
- W2061320431 cites W2132332248 @default.
- W2061320431 cites W2134728059 @default.
- W2061320431 cites W2136313738 @default.
- W2061320431 cites W2141221499 @default.
- W2061320431 cites W2141682571 @default.
- W2061320431 cites W2144534399 @default.
- W2061320431 cites W2144600435 @default.
- W2061320431 cites W2151877403 @default.
- W2061320431 cites W2161337232 @default.
- W2061320431 cites W2163573988 @default.
- W2061320431 cites W2167386790 @default.
- W2061320431 cites W2168051882 @default.
- W2061320431 cites W2170255248 @default.
- W2061320431 cites W2252785585 @default.
- W2061320431 cites W2404271688 @default.
- W2061320431 cites W2465805765 @default.
- W2061320431 cites W2787707700 @default.
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- W2061320431 doi "https://doi.org/10.1097/gco.0000000000000164" @default.
- W2061320431 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4590773" @default.
- W2061320431 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25719756" @default.
- W2061320431 hasPublicationYear "2015" @default.
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