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- W2061344906 abstract "Consumption of allylamine-HCl by Long-Evans rats of either sex for periods of 4–8 mo produces myocardial fibrosis with cardiac hypertrophy. Allylamine ingestion promotes focal edema and necrosis of smooth muscle cells in the media of coronary arteries but not in the pulmonary, renal or hepatic vessels. Appreciable hypertrophy of the auricles occurs only in hearts with moderate to extensive ventricular fibrosis. Hydralazine supplementation is able to inhibit induction of medial hyalinosis in the coronary arteries and myocardial fibrosis by allylamine. The mechanism which would account for the protective effect of hydralazine against the toxicity of allylamine is not known." @default.
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- W2061344906 date "1974-08-01" @default.
- W2061344906 modified "2023-09-28" @default.
- W2061344906 title "Influence of hydralazine consumption on allylamine induced myocardial fibrosis and hypertrophy in rats" @default.
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- W2061344906 doi "https://doi.org/10.1016/0014-4800(74)90076-8" @default.
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