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• W2061402824 abstract "Purpose of review: Traumatic articular cartilage injuries of the knee have an incidence of approximately 5%. Whether isolated or combined with ligamentous instability, meniscal pathology, or mechanical malalignment, these injuries can be quite debilitating for patients. Left untreated, patients experience pain, loss of motion, effusions, and eventual joint degeneration. Techniques such as autologous chondrocyte implantation show promise for regenerating tissue that closely resembles native hyaline articular cartilage. Recent findings: Recent themes in orthopaedic literature include improvements in imaging modalities, short-term and mid-term outcome results on surface replacement procedures, and future directions in basic science applications. Gene therapy, synthetic scaffolds, tissue engineering, and use of stimulatory factors such as bone morphogenic protein are some of the areas being researched. Summary: Advanced MRI along with a high index of suspicion allows the orthopaedist to identify and treat symptomatic articular cartilage defects in the knee. Short-term and mid-term results of surface replacement procedures such as autologous chondrocyte implantation are encouraging. With basic science research in areas such as tissue scaffolding, improvements in current treatment and new directions for future treatment are anticipated." @default.
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• W2061402824 date "2004-04-01" @default.
• W2061402824 modified "2023-10-14" @default.
• W2061402824 title "Treatment of knee articular cartilage injuries" @default.
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• W2061402824 doi "https://doi.org/10.1097/00001433-200404000-00009" @default.
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