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- W2061433174 abstract "TraR is an Agrobacterium transcriptional regulator whose activity requires the pheromone N-3-oxooctanoyl-L-homoserine lactone. TraR was purified as a complex with the pheromone and contained one pheromone molecule per protein monomer. TraR-pheromone complexes bound to a single DNA site and activated two promoters that flank this site. Promoter expression was elevated 30-fold by using a supercoiled template. Pheromone binding increased the affinity of TraR for this binding site. Pheromone also increased TraR abundance in vivo by causing a 20-fold decrease in TraR turnover rates." @default.
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- W2061433174 date "1999-04-27" @default.
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- W2061433174 title "Autoinducer binding by the quorum-sensing regulator TraR increases affinity for target promoters <i>in vitro</i> and decreases TraR turnover rates in whole cells" @default.
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- W2061433174 doi "https://doi.org/10.1073/pnas.96.9.4832" @default.
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