FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061488087> ?p ?o ?g. }

• W2061488087 endingPage "87" @default.
• W2061488087 startingPage "83" @default.
• W2061488087 abstract "There is evidence that dietary fat can modify the cytotoxicity of polychlorinated biphenyls (PCBs) and that coplanar PCBs can induce inflammatory processes critical in the pathology of vascular diseases. To test the hypothesis that the interaction of PCBs with dietary fat is dependent on the type of fat, low-density lipoprotein receptor-deficient (LDL-R(-/-)) mice were fed diets enriched with either olive oil or corn oil for 4 weeks. Half of the animals from each group were injected with PCB-77. Vascular cell adhesion molecule-1 (VCAM-1) expression in aortic arches was nondetectable in the olive-oil-fed mice but was highly expressed in the presence of PCB-77. PCB treatment increased liver neutral lipids and decreased serum fatty acid levels only in mice fed the corn-oil-enriched diet. PCB treatment increased mRNA expression of genes involved in inflammation, apoptosis, and oxidative stress in all mice. Upon PCB treatment, mice in both olive- and corn-oil-diet groups showed induction of genes involved in fatty acid degradation but with up-regulation of different key enzymes. Genes involved in fatty acid synthesis were reduced only upon PCB treatment in corn-oil-fed mice, whereas lipid transport/export genes were altered in olive-oil-fed mice. These data suggest that dietary fat can modify changes in lipid metabolism induced by PCBs in serum and tissues. These findings have implications for understanding the interactions of nutrients with environmental contaminants on the pathology of inflammatory diseases such as atherosclerosis." @default.
• W2061488087 created "2016-06-24" @default.
• W2061488087 creator A5000648888 @default.
• W2061488087 creator A5012144186 @default.
• W2061488087 creator A5044645853 @default.
• W2061488087 creator A5044742086 @default.
• W2061488087 creator A5046293802 @default.
• W2061488087 creator A5065258484 @default.
• W2061488087 creator A5079061954 @default.
• W2061488087 date "2005-01-01" @default.
• W2061488087 modified "2023-10-12" @default.
• W2061488087 title "Dietary Fat Interacts with PCBs to Induce Changes in Lipid Metabolism in Mice Deficient in Low-Density Lipoprotein Receptor" @default.
• W2061488087 cites W161476485 @default.
• W2061488087 cites W1871942206 @default.
• W2061488087 cites W1967344340 @default.
• W2061488087 cites W1974275521 @default.
• W2061488087 cites W1980378672 @default.
• W2061488087 cites W1993335505 @default.
• W2061488087 cites W1996913975 @default.
• W2061488087 cites W1998546556 @default.
• W2061488087 cites W2013875520 @default.
• W2061488087 cites W2015536313 @default.
• W2061488087 cites W2021595727 @default.
• W2061488087 cites W2022796928 @default.
• W2061488087 cites W2023068131 @default.
• W2061488087 cites W2027602469 @default.
• W2061488087 cites W2054178406 @default.
• W2061488087 cites W2064774222 @default.
• W2061488087 cites W2073683019 @default.
• W2061488087 cites W2078161821 @default.
• W2061488087 cites W2080373577 @default.
• W2061488087 cites W2084727662 @default.
• W2061488087 cites W2091727215 @default.
• W2061488087 cites W2096338404 @default.
• W2061488087 cites W2098123343 @default.
• W2061488087 cites W2101002153 @default.
• W2061488087 cites W2109341297 @default.
• W2061488087 cites W2133870558 @default.
• W2061488087 cites W2135016146 @default.
• W2061488087 cites W2137200696 @default.
• W2061488087 cites W2152311269 @default.
• W2061488087 cites W2155024223 @default.
• W2061488087 cites W2489894748 @default.
• W2061488087 cites W368095129 @default.
• W2061488087 doi "https://doi.org/10.1289/ehp.7280" @default.
• W2061488087 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1253714" @default.
• W2061488087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15626652" @default.
• W2061488087 hasPublicationYear "2005" @default.
• W2061488087 type Work @default.
• W2061488087 sameAs 2061488087 @default.
• W2061488087 citedByCount "76" @default.
• W2061488087 countsByYear W20614880872012 @default.
• W2061488087 countsByYear W20614880872013 @default.
• W2061488087 countsByYear W20614880872014 @default.
• W2061488087 countsByYear W20614880872015 @default.
• W2061488087 countsByYear W20614880872016 @default.
• W2061488087 countsByYear W20614880872017 @default.
• W2061488087 countsByYear W20614880872018 @default.
• W2061488087 countsByYear W20614880872019 @default.
• W2061488087 countsByYear W20614880872020 @default.
• W2061488087 countsByYear W20614880872021 @default.
• W2061488087 countsByYear W20614880872022 @default.
• W2061488087 countsByYear W20614880872023 @default.
• W2061488087 crossrefType "journal-article" @default.
• W2061488087 hasAuthorship W2061488087A5000648888 @default.
• W2061488087 hasAuthorship W2061488087A5012144186 @default.
• W2061488087 hasAuthorship W2061488087A5044645853 @default.
• W2061488087 hasAuthorship W2061488087A5044742086 @default.
• W2061488087 hasAuthorship W2061488087A5046293802 @default.
• W2061488087 hasAuthorship W2061488087A5065258484 @default.
• W2061488087 hasAuthorship W2061488087A5079061954 @default.
• W2061488087 hasBestOaLocation W20614880871 @default.
• W2061488087 hasConcept C126322002 @default.
• W2061488087 hasConcept C134018914 @default.
• W2061488087 hasConcept C170493617 @default.
• W2061488087 hasConcept C185592680 @default.
• W2061488087 hasConcept C203014093 @default.
• W2061488087 hasConcept C2776151105 @default.
• W2061488087 hasConcept C2776914184 @default.
• W2061488087 hasConcept C2778163477 @default.
• W2061488087 hasConcept C2778206080 @default.
• W2061488087 hasConcept C2780072125 @default.
• W2061488087 hasConcept C43554185 @default.
• W2061488087 hasConcept C4733338 @default.
• W2061488087 hasConcept C543025807 @default.
• W2061488087 hasConcept C55493867 @default.
• W2061488087 hasConcept C71924100 @default.
• W2061488087 hasConcept C86803240 @default.
• W2061488087 hasConceptScore W2061488087C126322002 @default.
• W2061488087 hasConceptScore W2061488087C134018914 @default.
• W2061488087 hasConceptScore W2061488087C170493617 @default.
• W2061488087 hasConceptScore W2061488087C185592680 @default.
• W2061488087 hasConceptScore W2061488087C203014093 @default.
• W2061488087 hasConceptScore W2061488087C2776151105 @default.
• W2061488087 hasConceptScore W2061488087C2776914184 @default.
• W2061488087 hasConceptScore W2061488087C2778163477 @default.
• W2061488087 hasConceptScore W2061488087C2778206080 @default.
• W2061488087 hasConceptScore W2061488087C2780072125 @default.

• next