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- W2061506768 abstract "Pars nervosa and pars intermedia in the hypophyses of the adult male albino rats fed in normal condition were observed with the electron microscope. In nerve terminals in the neural lobe, various steps of dissolution of neurosecretory substance could be observed. Neurosecretory axons may appear completely surrounded by the cytoplasm of a pituicyte. It is not certain whether the axon may completely pierce through the pituicyte or not. Similar invasion of axons with or without secretory granules occurs into the glandular (epithelial) cells of the pars intermedia. This finding may serve as ultrastructural evidence of one of the ways through which the neurosecretory substance may be transported from the neuro- to the adenohypophysis. The neurosecretory granules exclusively appear inside the axons, and no isolated granule can be observed in the pituicyte and intermedia cells, nor in the intercellular spaces in the both lobes. The secretion has apparently been dissolved prior to the discharge and after that it is no longer electron dense. Small numbers of dense granules, probably of secretion, were observed at the Golgi apparatus of the light cells of pars intermedia, suggesting secretory activities which have not been completely clarified at the present state of investigation. Ciliated cells could be seen at the marginal zone of the pars intermedia facing the residual lumen of Rathke. The arrangement of cilia is frequently irregular, but their ultrastructures are the same as those of kinocilia of ciliated epithelium hitherto reported." @default.
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- W2061506768 date "1961-12-01" @default.
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- W2061506768 title "Electron microscope studies on the fine structures of the pars nervosa and pars intermedia, and their morphological interrelation in the normal rat hypophysis" @default.
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- W2061506768 doi "https://doi.org/10.1016/0016-6480(61)90007-7" @default.
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