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- W2061517844 abstract "The lichen-derived natural products, atranorin (1), hopane-6α, 22-diol (2), usnic acid (3), and vulpinic acid (4) were analysed by both one and two-dimensional (1H, 13C)-NMR. Experiments employed included COSY, NOESY, XHCO, HMQC and HMBC. For 1 and 2, fully assigned proton NMR data are reported for the first time; the reassigned 13C NMR data for both 1 and 2 are also reported. For 3, cross-peaks were observed in the HMBC spectrum that suggest that CH long-range coupling through H bonds is occurring. Biological activity investigations of each compound indicated hopane-6α, 22-diol (2) to have anti-tubercular activity (MIC 8 µg/mL) and usnic acid (3) to be very weakly cytotoxic (ED50 13 µg/mL). Copyright © 1999 John Wiley & Sons, Ltd." @default.
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- W2061517844 date "1999-09-01" @default.
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- W2061517844 title "1H and13C-NMR and biological activity investigations of four lichen-derived compounds" @default.
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- W2061517844 doi "https://doi.org/10.1002/(sici)1099-1565(199909/10)10:5<279::aid-pca464>3.0.co;2-3" @default.
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