FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061523903> ?p ?o ?g. }

• W2061523903 endingPage "2649" @default.
• W2061523903 startingPage "2639" @default.
• W2061523903 abstract "Although genomic instability is a hallmark of human cancer cells, the mechanisms by which genomic instability is generated and selected for during oncogenesis remain obscure. In most human cancers, the pathway leading to the activation of the G1 cyclins is deregulated. Using budding yeast as a model, we show that overexpression of the G1 cyclin Cln2 inhibits the assembly of prereplicative complexes (pre-RCs) and induces gross chromosome rearrangements (GCR). Our results suggest that deregulation of G1 cyclins, selected for in oncogenesis because it confers clonal growth advantage, may also provide an important mechanism for generating genomic instability by inhibiting replication licensing." @default.
• W2061523903 created "2016-06-24" @default.
• W2061523903 creator A5029333589 @default.
• W2061523903 creator A5081256427 @default.
• W2061523903 date "2002-10-15" @default.
• W2061523903 modified "2023-09-23" @default.
• W2061523903 title "Deregulated G₁-cyclin expression induces genomic instability by preventing efficient pre-RC formation" @default.
• W2061523903 cites W1480404031 @default.
• W2061523903 cites W1483473129 @default.
• W2061523903 cites W1493317669 @default.
• W2061523903 cites W1500930737 @default.
• W2061523903 cites W1506793089 @default.
• W2061523903 cites W1569755992 @default.
• W2061523903 cites W1579620269 @default.
• W2061523903 cites W1609607086 @default.
• W2061523903 cites W1676311359 @default.
• W2061523903 cites W1778446120 @default.
• W2061523903 cites W1862994794 @default.
• W2061523903 cites W1912789001 @default.
• W2061523903 cites W1962559236 @default.
• W2061523903 cites W1964429281 @default.
• W2061523903 cites W1967579846 @default.
• W2061523903 cites W1968074226 @default.
• W2061523903 cites W1970591729 @default.
• W2061523903 cites W1971079672 @default.
• W2061523903 cites W1973428920 @default.
• W2061523903 cites W1981391513 @default.
• W2061523903 cites W1981802723 @default.
• W2061523903 cites W1987907353 @default.
• W2061523903 cites W1988243100 @default.
• W2061523903 cites W1989842611 @default.
• W2061523903 cites W1992334813 @default.
• W2061523903 cites W1993464551 @default.
• W2061523903 cites W2005353346 @default.
• W2061523903 cites W2007618242 @default.
• W2061523903 cites W2008136020 @default.
• W2061523903 cites W2014354746 @default.
• W2061523903 cites W2017816163 @default.
• W2061523903 cites W2019238772 @default.
• W2061523903 cites W2019808923 @default.
• W2061523903 cites W2026160273 @default.
• W2061523903 cites W2034811570 @default.
• W2061523903 cites W2043247515 @default.
• W2061523903 cites W2047746661 @default.
• W2061523903 cites W2048599311 @default.
• W2061523903 cites W2050173515 @default.
• W2061523903 cites W2053104682 @default.
• W2061523903 cites W2057051052 @default.
• W2061523903 cites W2061562811 @default.
• W2061523903 cites W2065971145 @default.
• W2061523903 cites W2075408326 @default.
• W2061523903 cites W2082382637 @default.
• W2061523903 cites W2084350197 @default.
• W2061523903 cites W2088729221 @default.
• W2061523903 cites W2089042591 @default.
• W2061523903 cites W2090538417 @default.
• W2061523903 cites W2097164868 @default.
• W2061523903 cites W2097263662 @default.
• W2061523903 cites W2106130068 @default.
• W2061523903 cites W2110902629 @default.
• W2061523903 cites W2135166443 @default.
• W2061523903 cites W2143028761 @default.
• W2061523903 cites W2143955948 @default.
• W2061523903 cites W2144892831 @default.
• W2061523903 cites W2147251931 @default.
• W2061523903 cites W2151479322 @default.
• W2061523903 cites W2159331673 @default.
• W2061523903 cites W2161395266 @default.
• W2061523903 cites W2164864372 @default.
• W2061523903 cites W2316148317 @default.
• W2061523903 cites W2318781517 @default.
• W2061523903 cites W4302942746 @default.
• W2061523903 cites W71175735 @default.
• W2061523903 doi "https://doi.org/10.1101/gad.1011002" @default.
• W2061523903 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/187461" @default.
• W2061523903 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12381663" @default.
• W2061523903 hasPublicationYear "2002" @default.
• W2061523903 type Work @default.
• W2061523903 sameAs 2061523903 @default.
• W2061523903 citedByCount "148" @default.
• W2061523903 countsByYear W20615239032012 @default.
• W2061523903 countsByYear W20615239032013 @default.
• W2061523903 countsByYear W20615239032014 @default.
• W2061523903 countsByYear W20615239032015 @default.
• W2061523903 countsByYear W20615239032016 @default.
• W2061523903 countsByYear W20615239032017 @default.
• W2061523903 countsByYear W20615239032018 @default.
• W2061523903 countsByYear W20615239032019 @default.
• W2061523903 countsByYear W20615239032020 @default.
• W2061523903 countsByYear W20615239032021 @default.
• W2061523903 countsByYear W20615239032022 @default.
• W2061523903 countsByYear W20615239032023 @default.
• W2061523903 crossrefType "journal-article" @default.
• W2061523903 hasAuthorship W2061523903A5029333589 @default.
• W2061523903 hasAuthorship W2061523903A5081256427 @default.
• W2061523903 hasBestOaLocation W20615239031 @default.
• W2061523903 hasConcept C104317684 @default.
• W2061523903 hasConcept C11882975 @default.

• next