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• W2061547898 abstract "Recently, we reported the spectroscopic and kinetic characterizations of cytochrome P450 compound I in CYP119A1, effectively closing the catalytic cycle of cytochrome P450-mediated hydroxylations. In this minireview, we focus on the developments that made this breakthrough possible. We examine the importance of enzyme purification in the quest for reactive intermediates and report the preparation of compound I in a second P450 (P450ST). In an effort to bring clarity to the field, we also examine the validity of controversial reports claiming the production of P450 compound I through the use of peroxynitrite and laser flash photolysis." @default.
• W2061547898 created "2016-06-24" @default.
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• W2061547898 date "2013-06-01" @default.
• W2061547898 modified "2023-10-12" @default.
• W2061547898 title "Reactive Intermediates in Cytochrome P450 Catalysis" @default.
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• W2061547898 doi "https://doi.org/10.1074/jbc.r113.473108" @default.
• W2061547898 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3682513" @default.
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• W2061547898 hasPublicationYear "2013" @default.
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