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- W2061551608 abstract "To propose an in vivo confocal microscopic scoring system for evaluation of irritant-induced corneal changes.Rat corneas were instilled with 0.01-0.5% benzalkonium chloride (BAC) and examined using high-resolution in vivo confocal microscopy (HRT-II) to measure corneal thickness and characterize corneal damage patterns. Severity scores were given for each predefined evaluation parameter and then totaled.The scoring system revealed a dose-dependent effect of BAC and discriminated between high- and low-dose treatments.This HRT-II scoring standardizes damage evaluation at the cellular level, even when assessing irritating compounds at low concentrations." @default.
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- W2061551608 date "2008-01-01" @default.
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- W2061551608 title "<i>In Vivo</i>Confocal Microscopic Grading System for Standardized Corneal Evaluation: Application to Toxic-Induced Damage in Rat" @default.
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- W2061551608 doi "https://doi.org/10.1080/02713680802381460" @default.
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