FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061563493> ?p ?o ?g. }

• W2061563493 endingPage "143" @default.
• W2061563493 startingPage "137" @default.
• W2061563493 abstract "Background Left bundle branch block (LBBB) leads to prolonged left ventricular (LV) total activation time (TAT) and ventricular electrical uncoupling (VEU; mean LV activation time minus mean right ventricular [RV] activation time); both have been shown to be preferential targets for cardiac resynchronization therapy (CRT). Whether right ventricular apical pacing (RVAP) produces similar ventricular activation patterns has not been well studied. Objective The purpose of this study was to compare electrical ventricular activation patterns during RVAP and LBBB. Methods We performed ECG mapping during sinus rhythm, RVAP, and CRT in 24 patients with LBBB. Results We observed differences in the electrical activation pattern with RVAP compared to LBBB. During LBBB, RV activation occurred rapidly; in contrast, RV activation was prolonged during RVAP (46 ± 21 ms vs 69 ± 17 ms, P <.001). There was no significant difference in LVTAT; however, differences in conduction pattern were observed. During LBBB, LV activation was circumferential, whereas with RVAP, LV activation proceeded from apex to base. Differences in the number, size, and orientation of lines of slow conduction also were observed. With LBBB, VEU was nearly twice as long as during RVAP (73 ± 12 ms vs 38 ± 21 ms, P <.001). CRT resulted in a greater reduction in VEU relative to LBBB activation (P <.001). Conclusion RVAP produces significant differences in ventricular activation characteristics compared to LBBB. Significantly less VEU occurs with RVAP, and as a result CRT produces a smaller relative reduction in VEU. This may explain the finding that CRT appears to be more effective in patients with LBBB than in those who were upgraded because of high percentages of RV pacing. Left bundle branch block (LBBB) leads to prolonged left ventricular (LV) total activation time (TAT) and ventricular electrical uncoupling (VEU; mean LV activation time minus mean right ventricular [RV] activation time); both have been shown to be preferential targets for cardiac resynchronization therapy (CRT). Whether right ventricular apical pacing (RVAP) produces similar ventricular activation patterns has not been well studied. The purpose of this study was to compare electrical ventricular activation patterns during RVAP and LBBB. We performed ECG mapping during sinus rhythm, RVAP, and CRT in 24 patients with LBBB. We observed differences in the electrical activation pattern with RVAP compared to LBBB. During LBBB, RV activation occurred rapidly; in contrast, RV activation was prolonged during RVAP (46 ± 21 ms vs 69 ± 17 ms, P <.001). There was no significant difference in LVTAT; however, differences in conduction pattern were observed. During LBBB, LV activation was circumferential, whereas with RVAP, LV activation proceeded from apex to base. Differences in the number, size, and orientation of lines of slow conduction also were observed. With LBBB, VEU was nearly twice as long as during RVAP (73 ± 12 ms vs 38 ± 21 ms, P <.001). CRT resulted in a greater reduction in VEU relative to LBBB activation (P <.001). RVAP produces significant differences in ventricular activation characteristics compared to LBBB. Significantly less VEU occurs with RVAP, and as a result CRT produces a smaller relative reduction in VEU. This may explain the finding that CRT appears to be more effective in patients with LBBB than in those who were upgraded because of high percentages of RV pacing." @default.
• W2061563493 created "2016-06-24" @default.
• W2061563493 creator A5030282021 @default.
• W2061563493 creator A5034213745 @default.
• W2061563493 creator A5036210507 @default.
• W2061563493 creator A5055509099 @default.
• W2061563493 creator A5072424721 @default.
• W2061563493 creator A5074500241 @default.
• W2061563493 creator A5077457324 @default.
• W2061563493 creator A5081759988 @default.
• W2061563493 creator A5087349506 @default.
• W2061563493 creator A5089675674 @default.
• W2061563493 date "2015-01-01" @default.
• W2061563493 modified "2023-10-07" @default.
• W2061563493 title "Detailed analysis of ventricular activation sequences during right ventricular apical pacing and left bundle branch block and the potential implications for cardiac resynchronization therapy" @default.
• W2061563493 cites W117247478 @default.
• W2061563493 cites W1979408598 @default.
• W2061563493 cites W2001868779 @default.
• W2061563493 cites W2026768619 @default.
• W2061563493 cites W2035667813 @default.
• W2061563493 cites W2090808686 @default.
• W2061563493 cites W2094626355 @default.
• W2061563493 cites W2112473867 @default.
• W2061563493 cites W2128615233 @default.
• W2061563493 cites W2135533595 @default.
• W2061563493 cites W2136821936 @default.
• W2061563493 cites W2141895646 @default.
• W2061563493 cites W2146521529 @default.
• W2061563493 cites W2158173438 @default.
• W2061563493 cites W2166022387 @default.
• W2061563493 cites W2567948445 @default.
• W2061563493 cites W2614153041 @default.
• W2061563493 cites W3144470180 @default.
• W2061563493 cites W4211125439 @default.
• W2061563493 cites W4361868645 @default.
• W2061563493 doi "https://doi.org/10.1016/j.hrthm.2014.09.059" @default.
• W2061563493 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25285646" @default.
• W2061563493 hasPublicationYear "2015" @default.
• W2061563493 type Work @default.
• W2061563493 sameAs 2061563493 @default.
• W2061563493 citedByCount "32" @default.
• W2061563493 countsByYear W20615634932015 @default.
• W2061563493 countsByYear W20615634932016 @default.
• W2061563493 countsByYear W20615634932017 @default.
• W2061563493 countsByYear W20615634932018 @default.
• W2061563493 countsByYear W20615634932019 @default.
• W2061563493 countsByYear W20615634932020 @default.
• W2061563493 countsByYear W20615634932021 @default.
• W2061563493 countsByYear W20615634932022 @default.
• W2061563493 crossrefType "journal-article" @default.
• W2061563493 hasAuthorship W2061563493A5030282021 @default.
• W2061563493 hasAuthorship W2061563493A5034213745 @default.
• W2061563493 hasAuthorship W2061563493A5036210507 @default.
• W2061563493 hasAuthorship W2061563493A5055509099 @default.
• W2061563493 hasAuthorship W2061563493A5072424721 @default.
• W2061563493 hasAuthorship W2061563493A5074500241 @default.
• W2061563493 hasAuthorship W2061563493A5077457324 @default.
• W2061563493 hasAuthorship W2061563493A5081759988 @default.
• W2061563493 hasAuthorship W2061563493A5087349506 @default.
• W2061563493 hasAuthorship W2061563493A5089675674 @default.
• W2061563493 hasConcept C126322002 @default.
• W2061563493 hasConcept C164705383 @default.
• W2061563493 hasConcept C2775914520 @default.
• W2061563493 hasConcept C2776034619 @default.
• W2061563493 hasConcept C2777473070 @default.
• W2061563493 hasConcept C2778198053 @default.
• W2061563493 hasConcept C2779161974 @default.
• W2061563493 hasConcept C2993376042 @default.
• W2061563493 hasConcept C3020135794 @default.
• W2061563493 hasConcept C71924100 @default.
• W2061563493 hasConcept C78085059 @default.
• W2061563493 hasConceptScore W2061563493C126322002 @default.
• W2061563493 hasConceptScore W2061563493C164705383 @default.
• W2061563493 hasConceptScore W2061563493C2775914520 @default.
• W2061563493 hasConceptScore W2061563493C2776034619 @default.
• W2061563493 hasConceptScore W2061563493C2777473070 @default.
• W2061563493 hasConceptScore W2061563493C2778198053 @default.
• W2061563493 hasConceptScore W2061563493C2779161974 @default.
• W2061563493 hasConceptScore W2061563493C2993376042 @default.
• W2061563493 hasConceptScore W2061563493C3020135794 @default.
• W2061563493 hasConceptScore W2061563493C71924100 @default.
• W2061563493 hasConceptScore W2061563493C78085059 @default.
• W2061563493 hasIssue "1" @default.
• W2061563493 hasLocation W20615634931 @default.
• W2061563493 hasLocation W20615634932 @default.
• W2061563493 hasOpenAccess W2061563493 @default.
• W2061563493 hasPrimaryLocation W20615634931 @default.
• W2061563493 hasRelatedWork W2086924764 @default.
• W2061563493 hasRelatedWork W2122071169 @default.
• W2061563493 hasRelatedWork W2164090541 @default.
• W2061563493 hasRelatedWork W2404136385 @default.
• W2061563493 hasRelatedWork W2793045314 @default.
• W2061563493 hasRelatedWork W2799873433 @default.
• W2061563493 hasRelatedWork W3032016155 @default.
• W2061563493 hasRelatedWork W3049616741 @default.
• W2061563493 hasRelatedWork W4308182655 @default.
• W2061563493 hasRelatedWork W4386998864 @default.
• W2061563493 hasVolume "12" @default.

• next