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- W2061569274 abstract "Data on the experimental measurement of the octanol/water partition coefficient (Kow) with hydrophobic compounds was assembled from the literature. The precision, characterised by the standard deviation of mean Kow values based on five commonly used experimental methods, over an extended Kow range was found to generally decline with compounds having log Kow > 5.5. In the log Kow range from 2.0 to 5.5 there was little difference between the mean values of log Kow determined by the different methods but major differences occured with compounds having log Kow > 5.5. The agreement between calculated ClogP values and Kow values derived from individual experimental methods indicated that ClogP overestimates log Kow from all experimental methods with compounds having values greater than 5.5." @default.
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- W2061569274 date "1991-01-01" @default.
- W2061569274 modified "2023-10-16" @default.
- W2061569274 title "Critical evaluation of the measurement of the 1- octanol / water partition coefficient of hydrophobic compounds" @default.
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- W2061569274 doi "https://doi.org/10.1016/0045-6535(91)90213-w" @default.
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