FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061597573> ?p ?o ?g. }

• W2061597573 endingPage "9" @default.
• W2061597573 startingPage "1" @default.
• W2061597573 abstract "For 20 or more years it has been known that a single oral dose of 5 mg mestranol (17alpha-ethinylestradiol-2 methyl ether) is effective for preventing conception in the beagle 95% of the time when administered 1-5 days after mating. This study administered a single oral dose of 4.5, 1.5, or .5 mg on Day 5 after mating to 7 young beagle bitches. All were sacrificed on Days 21-28 after mating, the second trimester of pregnancy in this species. 5 of the 7 animals (those receiving .5 and 1.5 mg) had uteri containing degenerate embryos. In 1 animal receiving 1.5 mg, embryos had already disappeared. 1 bitch receiving 4.5 mg was probably not pregnant. In each instance the embryos were free-floating in the lumen of the uterus due to failure of placental attachment and were either retarded or degenerating. Histologically, the innermost lining of the maternal placenta was disrupted in focal areas with the aseptic lesion containing debris and necrotic cells. Areas between such disrupted areas were lined by the thickened wall of the blastocyst, suggesting resorption of the embryos. Plasma progesterone levels rose during the first trimester according to the pattern for beagles, indicating mestranol had no visible effect on ovarian progesterone production. The tentative conclusion is that mestranol dose not interfere with fertilization or early embryonic development but rather with implantation, resulting in resorption of degenerating embryos." @default.
• W2061597573 created "2016-06-24" @default.
• W2061597573 creator A5007228182 @default.
• W2061597573 creator A5070891888 @default.
• W2061597573 creator A5088776132 @default.
• W2061597573 date "1975-07-01" @default.
• W2061597573 modified "2023-09-25" @default.
• W2061597573 title "Mestranol as an abortifacient in the bitch" @default.
• W2061597573 cites W2037339111 @default.
• W2061597573 cites W2096658291 @default.
• W2061597573 cites W2237019224 @default.
• W2061597573 cites W2254595824 @default.
• W2061597573 cites W2409233316 @default.
• W2061597573 cites W2754519367 @default.
• W2061597573 cites W569910917 @default.
• W2061597573 cites W641285931 @default.
• W2061597573 cites W2056586441 @default.
• W2061597573 cites W2403291222 @default.
• W2061597573 cites W3149419749 @default.
• W2061597573 doi "https://doi.org/10.1016/0093-691x(75)90052-7" @default.
• W2061597573 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1222871" @default.
• W2061597573 hasPublicationYear "1975" @default.
• W2061597573 type Work @default.
• W2061597573 sameAs 2061597573 @default.
• W2061597573 citedByCount "8" @default.
• W2061597573 crossrefType "journal-article" @default.
• W2061597573 hasAuthorship W2061597573A5007228182 @default.
• W2061597573 hasAuthorship W2061597573A5070891888 @default.
• W2061597573 hasAuthorship W2061597573A5088776132 @default.
• W2061597573 hasConcept C112672928 @default.
• W2061597573 hasConcept C126322002 @default.
• W2061597573 hasConcept C134018914 @default.
• W2061597573 hasConcept C146562846 @default.
• W2061597573 hasConcept C16685009 @default.
• W2061597573 hasConcept C196843134 @default.
• W2061597573 hasConcept C1998276 @default.
• W2061597573 hasConcept C2776106523 @default.
• W2061597573 hasConcept C2776608385 @default.
• W2061597573 hasConcept C2776820430 @default.
• W2061597573 hasConcept C2778324911 @default.
• W2061597573 hasConcept C2779066055 @default.
• W2061597573 hasConcept C2779076696 @default.
• W2061597573 hasConcept C2779234561 @default.
• W2061597573 hasConcept C2779496863 @default.
• W2061597573 hasConcept C2779742232 @default.
• W2061597573 hasConcept C2908647359 @default.
• W2061597573 hasConcept C2986817661 @default.
• W2061597573 hasConcept C32253518 @default.
• W2061597573 hasConcept C42407357 @default.
• W2061597573 hasConcept C46973012 @default.
• W2061597573 hasConcept C54355233 @default.
• W2061597573 hasConcept C71924100 @default.
• W2061597573 hasConcept C86803240 @default.
• W2061597573 hasConcept C95444343 @default.
• W2061597573 hasConcept C99454951 @default.
• W2061597573 hasConceptScore W2061597573C112672928 @default.
• W2061597573 hasConceptScore W2061597573C126322002 @default.
• W2061597573 hasConceptScore W2061597573C134018914 @default.
• W2061597573 hasConceptScore W2061597573C146562846 @default.
• W2061597573 hasConceptScore W2061597573C16685009 @default.
• W2061597573 hasConceptScore W2061597573C196843134 @default.
• W2061597573 hasConceptScore W2061597573C1998276 @default.
• W2061597573 hasConceptScore W2061597573C2776106523 @default.
• W2061597573 hasConceptScore W2061597573C2776608385 @default.
• W2061597573 hasConceptScore W2061597573C2776820430 @default.
• W2061597573 hasConceptScore W2061597573C2778324911 @default.
• W2061597573 hasConceptScore W2061597573C2779066055 @default.
• W2061597573 hasConceptScore W2061597573C2779076696 @default.
• W2061597573 hasConceptScore W2061597573C2779234561 @default.
• W2061597573 hasConceptScore W2061597573C2779496863 @default.
• W2061597573 hasConceptScore W2061597573C2779742232 @default.
• W2061597573 hasConceptScore W2061597573C2908647359 @default.
• W2061597573 hasConceptScore W2061597573C2986817661 @default.
• W2061597573 hasConceptScore W2061597573C32253518 @default.
• W2061597573 hasConceptScore W2061597573C42407357 @default.
• W2061597573 hasConceptScore W2061597573C46973012 @default.
• W2061597573 hasConceptScore W2061597573C54355233 @default.
• W2061597573 hasConceptScore W2061597573C71924100 @default.
• W2061597573 hasConceptScore W2061597573C86803240 @default.
• W2061597573 hasConceptScore W2061597573C95444343 @default.
• W2061597573 hasConceptScore W2061597573C99454951 @default.
• W2061597573 hasIssue "1" @default.
• W2061597573 hasLocation W20615975731 @default.
• W2061597573 hasLocation W20615975732 @default.
• W2061597573 hasOpenAccess W2061597573 @default.
• W2061597573 hasPrimaryLocation W20615975731 @default.
• W2061597573 hasRelatedWork W1999224297 @default.
• W2061597573 hasRelatedWork W2046687927 @default.
• W2061597573 hasRelatedWork W2052864417 @default.
• W2061597573 hasRelatedWork W2056587126 @default.
• W2061597573 hasRelatedWork W2082854834 @default.
• W2061597573 hasRelatedWork W2107385636 @default.
• W2061597573 hasRelatedWork W2313211708 @default.
• W2061597573 hasRelatedWork W2376529337 @default.
• W2061597573 hasRelatedWork W2992490575 @default.
• W2061597573 hasRelatedWork W4323029305 @default.
• W2061597573 hasVolume "4" @default.
• W2061597573 isParatext "false" @default.

• next