Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061679189> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2061679189 endingPage "42" @default.
- W2061679189 startingPage "36" @default.
- W2061679189 abstract "Recent studies using preservative-free 2-chloroprocaine (2-CP) for spinal anesthesia have shown it to be a reliable short-acting agent in the 30-mg to 60-mg range. Investigations of doses below this range have not been performed.To establish the minimum effective dose for spinal anesthesia, this randomized, double-blind, crossover study investigates the characteristics of spinal 2-CP 10 mg and 20 mg in 8 volunteers and compares the results with previous data obtained for 30 to 60 mg in the same human model.Peak block height, regression to L1, tolerance to tourniquet, and transcutaneous electrical stimulation all increased with increasing doses from 10 to 60 mg ( P <.0001). Likewise, time to complete block regression, ambulation, and micturition also increased with increasing spinal 2-CP dosage ( P <.0001). Degree of motor block generally increased with increasing doses from 10 to 60 mg; however, no differences existed between the 20-mg and 30-mg and between the 40-mg and 60-mg doses.Spinal 2-CP 40 mg and 60 mg provide rapid and reliable sensory and motor block. Although the 20-mg and 30-mg doses can produce sensory anesthesia adequate for brief surgical procedures, less motor block and some sacral sparing should be anticipated. Because the 10-mg dose produces only brief and inconsistent sensory anesthesia, it can be considered a no-effect dose." @default.
- W2061679189 created "2016-06-24" @default.
- W2061679189 creator A5017800300 @default.
- W2061679189 date "2005-02-01" @default.
- W2061679189 modified "2023-10-10" @default.
- W2061679189 title "Spinal 2-chloroprocaine: Minimum effective dose" @default.
- W2061679189 cites W1638728775 @default.
- W2061679189 cites W1966394227 @default.
- W2061679189 cites W1973471270 @default.
- W2061679189 cites W1974669165 @default.
- W2061679189 cites W1978188593 @default.
- W2061679189 cites W1978222184 @default.
- W2061679189 cites W1988543027 @default.
- W2061679189 cites W1996867102 @default.
- W2061679189 cites W2000479292 @default.
- W2061679189 cites W2007615437 @default.
- W2061679189 cites W2036749799 @default.
- W2061679189 cites W2039134457 @default.
- W2061679189 cites W2041738170 @default.
- W2061679189 cites W2042778120 @default.
- W2061679189 cites W2044010295 @default.
- W2061679189 cites W2049308301 @default.
- W2061679189 cites W2070395513 @default.
- W2061679189 cites W2076304885 @default.
- W2061679189 cites W2080387083 @default.
- W2061679189 cites W2084409183 @default.
- W2061679189 cites W2086926810 @default.
- W2061679189 cites W2109086356 @default.
- W2061679189 cites W2139901276 @default.
- W2061679189 cites W2146691540 @default.
- W2061679189 cites W2168723051 @default.
- W2061679189 cites W2467971609 @default.
- W2061679189 doi "https://doi.org/10.1016/j.rapm.2004.09.008" @default.
- W2061679189 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15690266" @default.
- W2061679189 hasPublicationYear "2005" @default.
- W2061679189 type Work @default.
- W2061679189 sameAs 2061679189 @default.
- W2061679189 citedByCount "23" @default.
- W2061679189 countsByYear W20616791892012 @default.
- W2061679189 countsByYear W20616791892013 @default.
- W2061679189 countsByYear W20616791892014 @default.
- W2061679189 countsByYear W20616791892015 @default.
- W2061679189 countsByYear W20616791892019 @default.
- W2061679189 countsByYear W20616791892020 @default.
- W2061679189 countsByYear W20616791892021 @default.
- W2061679189 countsByYear W20616791892022 @default.
- W2061679189 crossrefType "journal-article" @default.
- W2061679189 hasAuthorship W2061679189A5017800300 @default.
- W2061679189 hasConcept C126322002 @default.
- W2061679189 hasConcept C142724271 @default.
- W2061679189 hasConcept C175768497 @default.
- W2061679189 hasConcept C204787440 @default.
- W2061679189 hasConcept C27081682 @default.
- W2061679189 hasConcept C2992037949 @default.
- W2061679189 hasConcept C2992886682 @default.
- W2061679189 hasConcept C42219234 @default.
- W2061679189 hasConcept C71924100 @default.
- W2061679189 hasConcept C77411442 @default.
- W2061679189 hasConcept C87813604 @default.
- W2061679189 hasConceptScore W2061679189C126322002 @default.
- W2061679189 hasConceptScore W2061679189C142724271 @default.
- W2061679189 hasConceptScore W2061679189C175768497 @default.
- W2061679189 hasConceptScore W2061679189C204787440 @default.
- W2061679189 hasConceptScore W2061679189C27081682 @default.
- W2061679189 hasConceptScore W2061679189C2992037949 @default.
- W2061679189 hasConceptScore W2061679189C2992886682 @default.
- W2061679189 hasConceptScore W2061679189C42219234 @default.
- W2061679189 hasConceptScore W2061679189C71924100 @default.
- W2061679189 hasConceptScore W2061679189C77411442 @default.
- W2061679189 hasConceptScore W2061679189C87813604 @default.
- W2061679189 hasIssue "1" @default.
- W2061679189 hasLocation W20616791891 @default.
- W2061679189 hasLocation W20616791892 @default.
- W2061679189 hasOpenAccess W2061679189 @default.
- W2061679189 hasPrimaryLocation W20616791891 @default.
- W2061679189 hasRelatedWork W2045288076 @default.
- W2061679189 hasRelatedWork W2120067176 @default.
- W2061679189 hasRelatedWork W2142850037 @default.
- W2061679189 hasRelatedWork W2329921393 @default.
- W2061679189 hasRelatedWork W2361913658 @default.
- W2061679189 hasRelatedWork W2374158321 @default.
- W2061679189 hasRelatedWork W2400539378 @default.
- W2061679189 hasRelatedWork W3117115818 @default.
- W2061679189 hasRelatedWork W4282046392 @default.
- W2061679189 hasRelatedWork W67671216 @default.
- W2061679189 hasVolume "30" @default.
- W2061679189 isParatext "false" @default.
- W2061679189 isRetracted "false" @default.
- W2061679189 magId "2061679189" @default.
- W2061679189 workType "article" @default.