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• W2061696313 abstract "<h3>Objective.</h3> —To determine the extent and severity of illness and mode of transmission of Chlamydia pneumoniae infection in 3 nursing home outbreaks. <h3>Design and Setting.</h3> —Retrospective cohort study in 3 nursing homes in Ontario from September to November 1994. <h3>Subjects.</h3> —A total of 549 residents and 65 staff members. <h3>Main Outcome Measures.</h3> —Morbidity and mortality were determined by a review of disease surveillance forms, residents' charts, and a self-administered questionnaire to staff. Single and paired serum samples for<i>C pneumoniae</i>serological testing and nasopharyngeal swabs for<i>Cpneumoniae</i>culture were collected, and direct fluorescent antibody assays were performed to confirm<i>C pneumoniae</i>infection. <h3>Results.</h3> —The attack rates for confirmed and suspected cases combined were 68%, 46%, and 44% among residents in nursing homes A, B, and C, respectively, and 34% among nursing home C staff. A total of 16 cases of pneumonia confirmed by chest x-ray and 6 deaths were identified. The spectrum of illness among nursing home C residents included a new cough in 58 (100%), fever in 37 (64%), sore throat in 14 (24%), and hoarseness in 8 (14%). Staff members at nursing home C were more likely to report hoarseness (P<.001) and sore throat (P<.001). Residents who smoked had onset of illness earlier than nonsmokers (P=.007), which perhaps is related to airborne transmission in a designated smoking room. <h3>Conclusions.</h3> —<i>Chlamydia pneumoniae</i>caused serious morbidity and mortality among residents and morbidity among staff;<i>Cpneumoniae</i>is an important cause of respiratory disease outbreaks in nursing homes, and diagnostic tests must be readily available for early recognition of<i>C pneumoniae</i>infections." @default.
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• W2061696313 date "1997-04-16" @default.
• W2061696313 modified "2023-09-26" @default.
• W2061696313 title "Chlamydia pneumoniae as a New Source of Infectious Outbreaks in Nursing Homes" @default.
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• W2061696313 doi "https://doi.org/10.1001/jama.1997.03540390044033" @default.
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