Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061764495> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2061764495 endingPage "263" @default.
- W2061764495 startingPage "260" @default.
- W2061764495 abstract "The present study tests the hypothesis that agents known to elevate the level of intracellular cyclic adenine nucleotide may direct different epithelial cells onto a pathway of epidermoid (squamous) development and differentiation. We report here that the mixture of dibutyryl cyclic AMP (dbcAMP), prostaglandins E1, E2 and B1 (PG E1, E2, B1), and papaverine (pap) enhances the rate of normal squamous cell development in organ-cultured skin of chick embryos. The three components may act synergistically to elevate the level of intracellular cyclic adenine nucleotide. We recently reported that the same group of agents induces abnormal development (squamous metaplasia) and aberrant differentiation (keratin production) in the normally cuboidal epithelium of cultured whole mammary glands of mice [1]. Thus, dbcAMP, PG E1, E2, B1, and pap are effective in enhancing normal squamous cell development and also in inducing squamous metaplasia de novo in the epithelial components of two different organs of embryonic and adult animals of two classes of vertebrates. The combined findings are suggestive that cyclic adenine nucleotide together with the prostaglandins may act generally on diverse types of epithelia to bring about squamous cell development and a differentiation marked by keratin production." @default.
- W2061764495 created "2016-06-24" @default.
- W2061764495 creator A5015079621 @default.
- W2061764495 creator A5021485368 @default.
- W2061764495 creator A5051755869 @default.
- W2061764495 date "1981-12-01" @default.
- W2061764495 modified "2023-09-24" @default.
- W2061764495 title "Enhancement of Squamous Cell Development in Cultured Skin by Cyclic Adenine Nucleotide and Prostaglandins" @default.
- W2061764495 cites W1556609434 @default.
- W2061764495 cites W1908858013 @default.
- W2061764495 cites W1972720420 @default.
- W2061764495 cites W1977623868 @default.
- W2061764495 cites W1985060738 @default.
- W2061764495 cites W1987711437 @default.
- W2061764495 cites W2003113478 @default.
- W2061764495 cites W2010555485 @default.
- W2061764495 cites W2030339563 @default.
- W2061764495 cites W2030587430 @default.
- W2061764495 cites W2039066776 @default.
- W2061764495 cites W2056971358 @default.
- W2061764495 cites W2059300208 @default.
- W2061764495 cites W2062145172 @default.
- W2061764495 cites W2069161066 @default.
- W2061764495 cites W2071280094 @default.
- W2061764495 cites W2075363755 @default.
- W2061764495 cites W2076566467 @default.
- W2061764495 cites W2090409150 @default.
- W2061764495 cites W2094986016 @default.
- W2061764495 cites W2110323479 @default.
- W2061764495 cites W2115645802 @default.
- W2061764495 cites W2132132718 @default.
- W2061764495 cites W2222836159 @default.
- W2061764495 doi "https://doi.org/10.1111/j.1432-0436.1981.tb01181.x" @default.
- W2061764495 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6279464" @default.
- W2061764495 hasPublicationYear "1981" @default.
- W2061764495 type Work @default.
- W2061764495 sameAs 2061764495 @default.
- W2061764495 citedByCount "8" @default.
- W2061764495 crossrefType "journal-article" @default.
- W2061764495 hasAuthorship W2061764495A5015079621 @default.
- W2061764495 hasAuthorship W2061764495A5021485368 @default.
- W2061764495 hasAuthorship W2061764495A5051755869 @default.
- W2061764495 hasConcept C104317684 @default.
- W2061764495 hasConcept C126322002 @default.
- W2061764495 hasConcept C134018914 @default.
- W2061764495 hasConcept C148738053 @default.
- W2061764495 hasConcept C1491633281 @default.
- W2061764495 hasConcept C2778524494 @default.
- W2061764495 hasConcept C2778981785 @default.
- W2061764495 hasConcept C512185932 @default.
- W2061764495 hasConcept C529295009 @default.
- W2061764495 hasConcept C54355233 @default.
- W2061764495 hasConcept C55493867 @default.
- W2061764495 hasConcept C71924100 @default.
- W2061764495 hasConcept C79879829 @default.
- W2061764495 hasConcept C81241287 @default.
- W2061764495 hasConcept C86803240 @default.
- W2061764495 hasConcept C95444343 @default.
- W2061764495 hasConceptScore W2061764495C104317684 @default.
- W2061764495 hasConceptScore W2061764495C126322002 @default.
- W2061764495 hasConceptScore W2061764495C134018914 @default.
- W2061764495 hasConceptScore W2061764495C148738053 @default.
- W2061764495 hasConceptScore W2061764495C1491633281 @default.
- W2061764495 hasConceptScore W2061764495C2778524494 @default.
- W2061764495 hasConceptScore W2061764495C2778981785 @default.
- W2061764495 hasConceptScore W2061764495C512185932 @default.
- W2061764495 hasConceptScore W2061764495C529295009 @default.
- W2061764495 hasConceptScore W2061764495C54355233 @default.
- W2061764495 hasConceptScore W2061764495C55493867 @default.
- W2061764495 hasConceptScore W2061764495C71924100 @default.
- W2061764495 hasConceptScore W2061764495C79879829 @default.
- W2061764495 hasConceptScore W2061764495C81241287 @default.
- W2061764495 hasConceptScore W2061764495C86803240 @default.
- W2061764495 hasConceptScore W2061764495C95444343 @default.
- W2061764495 hasIssue "1-3" @default.
- W2061764495 hasLocation W20617644951 @default.
- W2061764495 hasLocation W20617644952 @default.
- W2061764495 hasOpenAccess W2061764495 @default.
- W2061764495 hasPrimaryLocation W20617644951 @default.
- W2061764495 hasRelatedWork W1499643443 @default.
- W2061764495 hasRelatedWork W1979044496 @default.
- W2061764495 hasRelatedWork W1990387475 @default.
- W2061764495 hasRelatedWork W2045124968 @default.
- W2061764495 hasRelatedWork W2048828554 @default.
- W2061764495 hasRelatedWork W2067735178 @default.
- W2061764495 hasRelatedWork W2089348139 @default.
- W2061764495 hasRelatedWork W2118724423 @default.
- W2061764495 hasRelatedWork W2318725020 @default.
- W2061764495 hasRelatedWork W2407785312 @default.
- W2061764495 hasVolume "20" @default.
- W2061764495 isParatext "false" @default.
- W2061764495 isRetracted "false" @default.
- W2061764495 magId "2061764495" @default.
- W2061764495 workType "article" @default.