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- W2061796670 abstract "Knowledge of the physiology of the nitrites is much confused. This may be attributed in part to the previous lack of a test sufficiently sensitive yet specific for detecting the presence of or measuring extremely minute quantities of nitrite. Very minute doses of nitrite have profound physiologic effects. Although an immense amount of investigation has yielded many significant observations, many enigmas still remain unsolved in this complex field. Glyceryl trinitrate was discovered by Sobrero 1 in 1847, and the first physiologic studies on nitrites were initiated. Since then the accumulated literature has become enormous, and only a few significant papers can be reviewed here. Early analytic studies 2 revealed nitrite in many tissues but in some only after the tissues were ground. Liver reduces nitrate to nitrite. 3 The mechanism of this reduction is not definitely determined, but a vital process is presumably involved because this reduction is completely abolished" @default.
- W2061796670 created "2016-06-24" @default.
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- W2061796670 date "1937-04-01" @default.
- W2061796670 modified "2023-10-14" @default.
- W2061796670 title "THE BLOOD NITRITE" @default.
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- W2061796670 doi "https://doi.org/10.1001/archinte.1937.00170200062005" @default.
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