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• W2061804920 abstract "Eosinophilic granulocytes from the blood of patients with parasitic diseases were preincubated in the presence or absence of beta-interferon (beta-IFN). The number of cells bearing IgG-Fc receptors was determined by rosette formation with chicken erythrocytes coated with IgG antibodies. beta-IFN augmented the expression of IgG-Fc receptors on the cells within 1 h incubation. Treatment of beta-IFN with heat or acid did not abolish the activity. The doses of beta-IFN needed to induce the modulations of IgG-Fc receptors could also augment the eosinophil-mediated antibody-dependent cytotoxicity (ADCC) against chicken red blood cells which resulted most pronounced when the IgG antibodies were present in suboptimal amount. These data suggest the role of beta-IFN in the host resistance to parasitic diseases, mainly in the initial phases of parasitic infestation when the specific IgG antibody levels are very low." @default.
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• W2061804920 date "1986-01-01" @default.
• W2061804920 modified "2023-09-30" @default.
• W2061804920 title "Human eosinophils and parasitic diseases — III. β-interferon increases eosinophil IgG-Fc receptor expression and capacity" @default.
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• W2061804920 doi "https://doi.org/10.1016/0192-0561(86)90043-3" @default.
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