FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061807621> ?p ?o ?g. }

• W2061807621 endingPage "274" @default.
• W2061807621 startingPage "263" @default.
• W2061807621 abstract "Chondroitin sulfate proteoglycans are widespread extracellular matrix proteins and are specifically upregulated after CNS injury at the lesion site. Many proteoglycan core proteins have been described in the rat brain, but detailed analysis of individual proteoglycans expressed after injury are missing. The present study represents an initial attempt to assess the diversity and timing of lesion-induced expression of proteoglycans in order to elucidate their functional role in CNS injury and repair. Using immunocytochemical methods we analysed the expression of decorin and biglycan in the transected postcommissural fornix of the adult rat. Transection of the fornix induced the upregulation of both decorin and biglycan. However, their expression differed with respect to time course, regional extent and cellular localization. The rapid upregulation of decorin within a wide area around the lesion was followed by a massive appearance of biglycan that remained restricted to the transection site. Three months after lesion, differences of the area size of decorin- and biglycan-immunoreactivities were no longer detectable. Both proteoglycans were restricted to the lesion site and the fornix stumps. While decorin was primarily expressed by astrocytes, biglycan was deposited extracellularly in sheet-like structures. The upregulation of both proteoglycans persisted for at least up to 6 months after lesion. These strong but divergent lesion-induced expression patterns indicate important but different roles of decorin and biglycan in CNS injury." @default.
• W2061807621 created "2016-06-24" @default.
• W2061807621 creator A5006144687 @default.
• W2061807621 creator A5010196429 @default.
• W2061807621 creator A5028177835 @default.
• W2061807621 creator A5032709451 @default.
• W2061807621 creator A5040957636 @default.
• W2061807621 creator A5048195095 @default.
• W2061807621 date "1995-12-01" @default.
• W2061807621 modified "2023-10-18" @default.
• W2061807621 title "Differential expression of the small chondroitin/dermatan sulfate proteoglycans decorin and biglycan after injury of the adult rat brain" @default.
• W2061807621 cites W1504348021 @default.
• W2061807621 cites W1515550479 @default.
• W2061807621 cites W1544527238 @default.
• W2061807621 cites W1568329054 @default.
• W2061807621 cites W1573262794 @default.
• W2061807621 cites W1585182990 @default.
• W2061807621 cites W1624294703 @default.
• W2061807621 cites W1859477582 @default.
• W2061807621 cites W1966538134 @default.
• W2061807621 cites W1971236887 @default.
• W2061807621 cites W1975089000 @default.
• W2061807621 cites W1978031202 @default.
• W2061807621 cites W1992308841 @default.
• W2061807621 cites W2006184315 @default.
• W2061807621 cites W2013470697 @default.
• W2061807621 cites W2017398540 @default.
• W2061807621 cites W2017594099 @default.
• W2061807621 cites W2021038929 @default.
• W2061807621 cites W2023153142 @default.
• W2061807621 cites W2024727973 @default.
• W2061807621 cites W2025778924 @default.
• W2061807621 cites W2030429558 @default.
• W2061807621 cites W2031325850 @default.
• W2061807621 cites W2032304318 @default.
• W2061807621 cites W2037466352 @default.
• W2061807621 cites W2041345827 @default.
• W2061807621 cites W2051250763 @default.
• W2061807621 cites W2052918221 @default.
• W2061807621 cites W2053352199 @default.
• W2061807621 cites W2053681478 @default.
• W2061807621 cites W2071430673 @default.
• W2061807621 cites W2074306477 @default.
• W2061807621 cites W2077858087 @default.
• W2061807621 cites W2078687598 @default.
• W2061807621 cites W2080957836 @default.
• W2061807621 cites W2086679033 @default.
• W2061807621 cites W2092889119 @default.
• W2061807621 cites W2097530133 @default.
• W2061807621 cites W2120572145 @default.
• W2061807621 cites W2120596047 @default.
• W2061807621 cites W2122747866 @default.
• W2061807621 cites W2129591536 @default.
• W2061807621 cites W2130728604 @default.
• W2061807621 cites W2131651507 @default.
• W2061807621 cites W2136819827 @default.
• W2061807621 cites W2137171312 @default.
• W2061807621 cites W2141877739 @default.
• W2061807621 cites W2146559746 @default.
• W2061807621 cites W2151621078 @default.
• W2061807621 cites W2159375050 @default.
• W2061807621 cites W2166227856 @default.
• W2061807621 cites W2168391595 @default.
• W2061807621 cites W2178562205 @default.
• W2061807621 cites W3191436203 @default.
• W2061807621 cites W72057636 @default.
• W2061807621 doi "https://doi.org/10.1016/0006-8993(95)01131-5" @default.
• W2061807621 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8788923" @default.
• W2061807621 hasPublicationYear "1995" @default.
• W2061807621 type Work @default.
• W2061807621 sameAs 2061807621 @default.
• W2061807621 citedByCount "90" @default.
• W2061807621 countsByYear W20618076212012 @default.
• W2061807621 countsByYear W20618076212013 @default.
• W2061807621 countsByYear W20618076212014 @default.
• W2061807621 countsByYear W20618076212015 @default.
• W2061807621 countsByYear W20618076212016 @default.
• W2061807621 countsByYear W20618076212017 @default.
• W2061807621 countsByYear W20618076212018 @default.
• W2061807621 countsByYear W20618076212019 @default.
• W2061807621 countsByYear W20618076212021 @default.
• W2061807621 crossrefType "journal-article" @default.
• W2061807621 hasAuthorship W2061807621A5006144687 @default.
• W2061807621 hasAuthorship W2061807621A5010196429 @default.
• W2061807621 hasAuthorship W2061807621A5028177835 @default.
• W2061807621 hasAuthorship W2061807621A5032709451 @default.
• W2061807621 hasAuthorship W2061807621A5040957636 @default.
• W2061807621 hasAuthorship W2061807621A5048195095 @default.
• W2061807621 hasConcept C104317684 @default.
• W2061807621 hasConcept C105702510 @default.
• W2061807621 hasConcept C127561419 @default.
• W2061807621 hasConcept C142724271 @default.
• W2061807621 hasConcept C153074725 @default.
• W2061807621 hasConcept C169760540 @default.
• W2061807621 hasConcept C185592680 @default.
• W2061807621 hasConcept C189165786 @default.
• W2061807621 hasConcept C2775895372 @default.
• W2061807621 hasConcept C2778066728 @default.

• next