FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061812498> ?p ?o ?g. }

• W2061812498 endingPage "1818" @default.
• W2061812498 startingPage "1812" @default.
• W2061812498 abstract "We sought to evaluate the association between plasma levels of monocyte chemoattractant protein (MCP)-1 and the risk for subclinical atherosclerosis.Monocyte chemoattractant protein is a chemokine that recruits monocytes into the developing atheroma and may contribute to atherosclerotic disease development and progression. Plasma levels of MCP-1 are independently associated with prognosis in patients with acute coronary syndromes, but few population-based data are available from subjects in earlier stages of atherosclerosis.In the Dallas Heart Study, a population-based probability sample of adults in Dallas County </=65 years old, plasma levels of MCP-1 were measured in 3,499 subjects and correlated with traditional cardiovascular risk factors, high-sensitivity C-reactive protein (hs-CRP), and coronary artery calcium (CAC) measured by electron beam computed tomography.Higher MCP-1 levels were associated with older age, white race, family history of premature coronary disease, smoking, hypertension, diabetes, hypercholesterolemia, and higher levels of hs-CRP (p < 0.01 for each). Similar associations were observed between MCP-1 and risk factors in the subgroup of participants without detectable CAC. Compared with the subjects in the lowest quartile of MCP-1, the odds of prevalent CAC (CAC score >/=10) for subjects in the second, third, and fourth quartiles were 1.30 (95% confidence interval [CI] 0.99 to 1.73), 1.60 (95% CI 1.22 to 2.11), and 2.02 (95% CI 1.54 to 2.63), respectively. The association between MCP-1 and CAC remained significant when adjusted for traditional cardiovascular risk factors, but not when further adjusted for age.In a large population-based sample, plasma levels of MCP-1 were associated with traditional risk factors for atherosclerosis, supporting the hypothesis that MCP-1 may mediate some of the atherogenic effects of these risk factors. These findings support the potential role of MCP-1 as a biomarker target for drug development." @default.
• W2061812498 created "2016-06-24" @default.
• W2061812498 creator A5011768788 @default.
• W2061812498 creator A5017243866 @default.
• W2061812498 creator A5051212717 @default.
• W2061812498 creator A5058503662 @default.
• W2061812498 creator A5059631475 @default.
• W2061812498 creator A5071945904 @default.
• W2061812498 creator A5085897222 @default.
• W2061812498 date "2004-11-01" @default.
• W2061812498 modified "2023-09-26" @default.
• W2061812498 title "Association among plasma levels of monocyte chemoattractant protein-1, traditional cardiovascular risk factors, and subclinical atherosclerosis" @default.
• W2061812498 cites W192890715 @default.
• W2061812498 cites W1965574697 @default.
• W2061812498 cites W1967543638 @default.
• W2061812498 cites W1968668179 @default.
• W2061812498 cites W1978040433 @default.
• W2061812498 cites W1986610158 @default.
• W2061812498 cites W1988926553 @default.
• W2061812498 cites W2002329101 @default.
• W2061812498 cites W2006272818 @default.
• W2061812498 cites W2013718123 @default.
• W2061812498 cites W2016542625 @default.
• W2061812498 cites W2020693610 @default.
• W2061812498 cites W2021314070 @default.
• W2061812498 cites W2021656955 @default.
• W2061812498 cites W2024054271 @default.
• W2061812498 cites W2033199439 @default.
• W2061812498 cites W2036044006 @default.
• W2061812498 cites W2036852690 @default.
• W2061812498 cites W2038906796 @default.
• W2061812498 cites W2039643538 @default.
• W2061812498 cites W2051582311 @default.
• W2061812498 cites W2052704549 @default.
• W2061812498 cites W2077741802 @default.
• W2061812498 cites W2086269546 @default.
• W2061812498 cites W2087033359 @default.
• W2061812498 cites W2089939834 @default.
• W2061812498 cites W2094647069 @default.
• W2061812498 cites W2115163080 @default.
• W2061812498 cites W2117188544 @default.
• W2061812498 cites W2125589683 @default.
• W2061812498 cites W2153785016 @default.
• W2061812498 cites W2155191102 @default.
• W2061812498 cites W2156097706 @default.
• W2061812498 cites W2164807534 @default.
• W2061812498 cites W2170831198 @default.
• W2061812498 cites W2315984212 @default.
• W2061812498 doi "https://doi.org/10.1016/j.jacc.2004.07.047" @default.
• W2061812498 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15519012" @default.
• W2061812498 hasPublicationYear "2004" @default.
• W2061812498 type Work @default.
• W2061812498 sameAs 2061812498 @default.
• W2061812498 citedByCount "254" @default.
• W2061812498 countsByYear W20618124982012 @default.
• W2061812498 countsByYear W20618124982013 @default.
• W2061812498 countsByYear W20618124982014 @default.
• W2061812498 countsByYear W20618124982015 @default.
• W2061812498 countsByYear W20618124982016 @default.
• W2061812498 countsByYear W20618124982017 @default.
• W2061812498 countsByYear W20618124982018 @default.
• W2061812498 countsByYear W20618124982019 @default.
• W2061812498 countsByYear W20618124982020 @default.
• W2061812498 countsByYear W20618124982021 @default.
• W2061812498 countsByYear W20618124982022 @default.
• W2061812498 countsByYear W20618124982023 @default.
• W2061812498 crossrefType "journal-article" @default.
• W2061812498 hasAuthorship W2061812498A5011768788 @default.
• W2061812498 hasAuthorship W2061812498A5017243866 @default.
• W2061812498 hasAuthorship W2061812498A5051212717 @default.
• W2061812498 hasAuthorship W2061812498A5058503662 @default.
• W2061812498 hasAuthorship W2061812498A5059631475 @default.
• W2061812498 hasAuthorship W2061812498A5071945904 @default.
• W2061812498 hasAuthorship W2061812498A5085897222 @default.
• W2061812498 hasBestOaLocation W20618124981 @default.
• W2061812498 hasConcept C126322002 @default.
• W2061812498 hasConcept C134018914 @default.
• W2061812498 hasConcept C156957248 @default.
• W2061812498 hasConcept C164705383 @default.
• W2061812498 hasConcept C2776914184 @default.
• W2061812498 hasConcept C2778213512 @default.
• W2061812498 hasConcept C2779318932 @default.
• W2061812498 hasConcept C2781195455 @default.
• W2061812498 hasConcept C2908647359 @default.
• W2061812498 hasConcept C44249647 @default.
• W2061812498 hasConcept C555293320 @default.
• W2061812498 hasConcept C68443243 @default.
• W2061812498 hasConcept C71924100 @default.
• W2061812498 hasConcept C99454951 @default.
• W2061812498 hasConceptScore W2061812498C126322002 @default.
• W2061812498 hasConceptScore W2061812498C134018914 @default.
• W2061812498 hasConceptScore W2061812498C156957248 @default.
• W2061812498 hasConceptScore W2061812498C164705383 @default.
• W2061812498 hasConceptScore W2061812498C2776914184 @default.
• W2061812498 hasConceptScore W2061812498C2778213512 @default.
• W2061812498 hasConceptScore W2061812498C2779318932 @default.
• W2061812498 hasConceptScore W2061812498C2781195455 @default.
• W2061812498 hasConceptScore W2061812498C2908647359 @default.

• next