FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061844180> ?p ?o ?g. }

• W2061844180 endingPage "1918" @default.
• W2061844180 startingPage "1910" @default.
• W2061844180 abstract "Abstract Objective To define the musculoskeletal syndrome associated with use of aromatase inhibitors (AIs), specifically, to describe its incidence, time to onset, risk factors, and clinical presentation. Methods Postmenopausal women with hormone‐sensitive, nonmetastatic breast cancer starting AI therapy were enrolled in this prospective cohort study. They underwent complete rheumatologic evaluation and contrast‐enhanced magnetic resonance imaging (MRI) of the hands and wrists prior to starting AI, at 3 and 6 months. The primary outcome was change in grip strength. Results Twenty‐eight (54%) of 52 women reported new or worsening musculoskeletal symptoms. Two discontinued AIs due to pain. Mean time to symptom onset was 6 weeks (range 2–18 weeks), and 75% of symptomatic patients developed symptoms by 8 weeks. Later‐stage cancer and worse quality of life (QOL) pretreatment were significantly associated with symptom development. Sixty‐eight percent of symptomatic subjects had involvement of the hands; however, there was no difference in the mean change in grip strength (−2.9 kg versus −1.3 kg; P = 0.6). Among symptomatic subjects, 46% had evidence of focal tenosynovitis of the hands and feet on examination. Although some symptomatic subjects had new MRI abnormalities, Rheumatoid Arthritis Magnetic Resonance Imaging Scoring did not significantly change. Conclusion The incidence of AI‐associated musculoskeletal syndrome is more than 50%, with most women developing symptoms by 8 weeks. The key finding in symptomatic women was focal tenosynovitis of the hands and feet, without evidence of autoimmune disease or systemic inflammation. Later‐stage cancer and poorer QOL were predictive of symptom development." @default.
• W2061844180 created "2016-06-24" @default.
• W2061844180 creator A5004522625 @default.
• W2061844180 creator A5026919310 @default.
• W2061844180 creator A5027516550 @default.
• W2061844180 creator A5028522866 @default.
• W2061844180 creator A5062713436 @default.
• W2061844180 creator A5069035742 @default.
• W2061844180 creator A5075686685 @default.
• W2061844180 creator A5091621362 @default.
• W2061844180 date "2012-11-28" @default.
• W2061844180 modified "2023-10-17" @default.
• W2061844180 title "Defining the aromatase inhibitor musculoskeletal syndrome: A prospective study" @default.
• W2061844180 cites W1453600927 @default.
• W2061844180 cites W1964161175 @default.
• W2061844180 cites W1977708978 @default.
• W2061844180 cites W2009515050 @default.
• W2061844180 cites W2075077870 @default.
• W2061844180 cites W2089973119 @default.
• W2061844180 cites W2096446019 @default.
• W2061844180 cites W2101881391 @default.
• W2061844180 cites W2121656289 @default.
• W2061844180 cites W2124547747 @default.
• W2061844180 cites W2133764838 @default.
• W2061844180 cites W2140156103 @default.
• W2061844180 cites W2147993322 @default.
• W2061844180 cites W2148003100 @default.
• W2061844180 cites W2152142465 @default.
• W2061844180 cites W2167238270 @default.
• W2061844180 cites W2171213575 @default.
• W2061844180 cites W55130308 @default.
• W2061844180 doi "https://doi.org/10.1002/acr.21756" @default.
• W2061844180 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3504184" @default.
• W2061844180 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22730307" @default.
• W2061844180 hasPublicationYear "2012" @default.
• W2061844180 type Work @default.
• W2061844180 sameAs 2061844180 @default.
• W2061844180 citedByCount "31" @default.
• W2061844180 countsByYear W20618441802014 @default.
• W2061844180 countsByYear W20618441802015 @default.
• W2061844180 countsByYear W20618441802016 @default.
• W2061844180 countsByYear W20618441802017 @default.
• W2061844180 countsByYear W20618441802018 @default.
• W2061844180 countsByYear W20618441802019 @default.
• W2061844180 countsByYear W20618441802020 @default.
• W2061844180 countsByYear W20618441802021 @default.
• W2061844180 countsByYear W20618441802022 @default.
• W2061844180 countsByYear W20618441802023 @default.
• W2061844180 crossrefType "journal-article" @default.
• W2061844180 hasAuthorship W2061844180A5004522625 @default.
• W2061844180 hasAuthorship W2061844180A5026919310 @default.
• W2061844180 hasAuthorship W2061844180A5027516550 @default.
• W2061844180 hasAuthorship W2061844180A5028522866 @default.
• W2061844180 hasAuthorship W2061844180A5062713436 @default.
• W2061844180 hasAuthorship W2061844180A5069035742 @default.
• W2061844180 hasAuthorship W2061844180A5075686685 @default.
• W2061844180 hasAuthorship W2061844180A5091621362 @default.
• W2061844180 hasBestOaLocation W20618441801 @default.
• W2061844180 hasConcept C120665830 @default.
• W2061844180 hasConcept C121332964 @default.
• W2061844180 hasConcept C121608353 @default.
• W2061844180 hasConcept C126322002 @default.
• W2061844180 hasConcept C126838900 @default.
• W2061844180 hasConcept C141071460 @default.
• W2061844180 hasConcept C143409427 @default.
• W2061844180 hasConcept C159110408 @default.
• W2061844180 hasConcept C1862650 @default.
• W2061844180 hasConcept C188816634 @default.
• W2061844180 hasConcept C2776751720 @default.
• W2061844180 hasConcept C2777433710 @default.
• W2061844180 hasConcept C2777575956 @default.
• W2061844180 hasConcept C2779951463 @default.
• W2061844180 hasConcept C530470458 @default.
• W2061844180 hasConcept C61511704 @default.
• W2061844180 hasConcept C71924100 @default.
• W2061844180 hasConceptScore W2061844180C120665830 @default.
• W2061844180 hasConceptScore W2061844180C121332964 @default.
• W2061844180 hasConceptScore W2061844180C121608353 @default.
• W2061844180 hasConceptScore W2061844180C126322002 @default.
• W2061844180 hasConceptScore W2061844180C126838900 @default.
• W2061844180 hasConceptScore W2061844180C141071460 @default.
• W2061844180 hasConceptScore W2061844180C143409427 @default.
• W2061844180 hasConceptScore W2061844180C159110408 @default.
• W2061844180 hasConceptScore W2061844180C1862650 @default.
• W2061844180 hasConceptScore W2061844180C188816634 @default.
• W2061844180 hasConceptScore W2061844180C2776751720 @default.
• W2061844180 hasConceptScore W2061844180C2777433710 @default.
• W2061844180 hasConceptScore W2061844180C2777575956 @default.
• W2061844180 hasConceptScore W2061844180C2779951463 @default.
• W2061844180 hasConceptScore W2061844180C530470458 @default.
• W2061844180 hasConceptScore W2061844180C61511704 @default.
• W2061844180 hasConceptScore W2061844180C71924100 @default.
• W2061844180 hasIssue "12" @default.
• W2061844180 hasLocation W20618441801 @default.
• W2061844180 hasLocation W20618441802 @default.
• W2061844180 hasLocation W20618441803 @default.
• W2061844180 hasLocation W20618441804 @default.
• W2061844180 hasOpenAccess W2061844180 @default.

• next