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- W2061853605 abstract "The title compound, a mixture of two isomers differing in the position of a methoxy substituent in one benzene ring, was obtained in a Ni-templated synthesis directly as a water soluble dihydrochloride of the free base. The cyclic voltametry study indicated that in a neutral solution the reduction and oxidation are irreversible one electron processes, the latter leading to cation radical undergoing polymerization, a process followed by deposition of a film on the electrode. In 1,2-dichloroethane the cation radical is oxidized to a dication, both species being much less stable than those originating from meso-tetraphenylporphyrin. The title compoud at 2.5 × 10−5 M in Tris buffer showed a 50% inhibition of the growth of malignant melanoma cells as compared to a 44% inhibition shown by a water soluble meso-monomethoxy-tris(N-methylpyridinium)porphyrin. The exposure to light for 30 minutes at 2.5 times smaller concentration increased the inhibition caused by the pseudo-porphyrin from 9% to 49%." @default.
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- W2061853605 date "2010-08-20" @default.
- W2061853605 modified "2023-10-16" @default.
- W2061853605 title "ChemInform Abstract: 5,7,12,14-Tetramethyldimethoxybenzo(b,i)(1,4,8,11)tetraazacyclodecine, a New Tumoricidal Pseudo-porphyrin." @default.
- W2061853605 cites W2951755656 @default.
- W2061853605 doi "https://doi.org/10.1002/chin.199318234" @default.
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