Matches in SemOpenAlex for { <https://semopenalex.org/work/W2061874270> ?p ?o ?g. }
- W2061874270 endingPage "1120" @default.
- W2061874270 startingPage "1109" @default.
- W2061874270 abstract "Aim: The aim of this study was to assess whether rs1333049 was associated with coronary heart disease (CHD) in Han Chinese.Methods: This case-control study was involved with 599 CHD patients and 591 non-CHD controls. Meanwhile, a comprehensive meta-analysis was also conducted to establish the contribution of rs1333049 to CHD.Results: Our results showed that rs1333049 increased the risk of CHD by 38% (OR=1.38, 95% CI=1.18-1.62). A breakdown analysis by gender further indicated that rs1333049 increased the risk of CHD in men by 29% (OR=1.29, 95% CI=1.05-1.58) and in women by 64% (OR=1.64, 95% CI=1.25-2.16). A follow-up subgroup analysis by age showed there was a significant association between rs1333049 and CHD in women younger than 65 (≤55 years: p=0.001, 55-65 years: p=0.008) and in men aged between 55 and 65 years (p=0.005). Our meta-analysis was involved with 21 studies (25 stages) among 20969 cases and 34114 controls. Our results showed that rs1333049 led to a significantly increased risk of CHD (OR=1.30, 95% CI=1.21-1.39). Further subgroup analyses by ethnicity showed rs1333049 increased the CHD risk by 30% in Europeans (OR=1.30, 95% CI=1.16-1.47) and 27% in Asians (OR=1.27, 95% CI=1.22-1.33).Conclusions: Our case-control study and meta-analysis suggest that rs1333049 is a useful risk marker of CHD." @default.
- W2061874270 created "2016-06-24" @default.
- W2061874270 creator A5001537029 @default.
- W2061874270 creator A5001918918 @default.
- W2061874270 creator A5007538944 @default.
- W2061874270 creator A5017835570 @default.
- W2061874270 creator A5018863416 @default.
- W2061874270 creator A5021249077 @default.
- W2061874270 creator A5023205295 @default.
- W2061874270 creator A5032451703 @default.
- W2061874270 creator A5038033849 @default.
- W2061874270 creator A5040235944 @default.
- W2061874270 creator A5041832898 @default.
- W2061874270 creator A5053156190 @default.
- W2061874270 creator A5053968035 @default.
- W2061874270 creator A5055307257 @default.
- W2061874270 creator A5059105795 @default.
- W2061874270 creator A5059971691 @default.
- W2061874270 creator A5062261656 @default.
- W2061874270 creator A5064106247 @default.
- W2061874270 creator A5067015534 @default.
- W2061874270 creator A5074413224 @default.
- W2061874270 creator A5082012698 @default.
- W2061874270 creator A5085147583 @default.
- W2061874270 creator A5087032118 @default.
- W2061874270 date "2014-01-01" @default.
- W2061874270 modified "2023-09-30" @default.
- W2061874270 title "A Replication Study and a Meta-Analysis of the Association between the CDKN2A rs1333049 Polymorphism and Coronary Heart Disease" @default.
- W2061874270 cites W1499959019 @default.
- W2061874270 cites W1968176785 @default.
- W2061874270 cites W1971515763 @default.
- W2061874270 cites W1994515642 @default.
- W2061874270 cites W2015802439 @default.
- W2061874270 cites W2017137690 @default.
- W2061874270 cites W2017791285 @default.
- W2061874270 cites W2037231448 @default.
- W2061874270 cites W2046563081 @default.
- W2061874270 cites W2065891752 @default.
- W2061874270 cites W2069439027 @default.
- W2061874270 cites W2073576373 @default.
- W2061874270 cites W2074199852 @default.
- W2061874270 cites W2091126023 @default.
- W2061874270 cites W2091991738 @default.
- W2061874270 cites W2097504226 @default.
- W2061874270 cites W2098881762 @default.
- W2061874270 cites W2113103915 @default.
- W2061874270 cites W2120451046 @default.
- W2061874270 cites W2125895642 @default.
- W2061874270 cites W2136156766 @default.
- W2061874270 cites W2144062486 @default.
- W2061874270 cites W2148269820 @default.
- W2061874270 cites W2154088205 @default.
- W2061874270 cites W2166600376 @default.
- W2061874270 cites W2547258893 @default.
- W2061874270 cites W4256475235 @default.
- W2061874270 doi "https://doi.org/10.5551/jat.23507" @default.
- W2061874270 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24930384" @default.
- W2061874270 hasPublicationYear "2014" @default.
- W2061874270 type Work @default.
- W2061874270 sameAs 2061874270 @default.
- W2061874270 citedByCount "9" @default.
- W2061874270 countsByYear W20618742702016 @default.
- W2061874270 countsByYear W20618742702018 @default.
- W2061874270 countsByYear W20618742702019 @default.
- W2061874270 countsByYear W20618742702022 @default.
- W2061874270 crossrefType "journal-article" @default.
- W2061874270 hasAuthorship W2061874270A5001537029 @default.
- W2061874270 hasAuthorship W2061874270A5001918918 @default.
- W2061874270 hasAuthorship W2061874270A5007538944 @default.
- W2061874270 hasAuthorship W2061874270A5017835570 @default.
- W2061874270 hasAuthorship W2061874270A5018863416 @default.
- W2061874270 hasAuthorship W2061874270A5021249077 @default.
- W2061874270 hasAuthorship W2061874270A5023205295 @default.
- W2061874270 hasAuthorship W2061874270A5032451703 @default.
- W2061874270 hasAuthorship W2061874270A5038033849 @default.
- W2061874270 hasAuthorship W2061874270A5040235944 @default.
- W2061874270 hasAuthorship W2061874270A5041832898 @default.
- W2061874270 hasAuthorship W2061874270A5053156190 @default.
- W2061874270 hasAuthorship W2061874270A5053968035 @default.
- W2061874270 hasAuthorship W2061874270A5055307257 @default.
- W2061874270 hasAuthorship W2061874270A5059105795 @default.
- W2061874270 hasAuthorship W2061874270A5059971691 @default.
- W2061874270 hasAuthorship W2061874270A5062261656 @default.
- W2061874270 hasAuthorship W2061874270A5064106247 @default.
- W2061874270 hasAuthorship W2061874270A5067015534 @default.
- W2061874270 hasAuthorship W2061874270A5074413224 @default.
- W2061874270 hasAuthorship W2061874270A5082012698 @default.
- W2061874270 hasAuthorship W2061874270A5085147583 @default.
- W2061874270 hasAuthorship W2061874270A5087032118 @default.
- W2061874270 hasBestOaLocation W20618742701 @default.
- W2061874270 hasConcept C11783203 @default.
- W2061874270 hasConcept C126322002 @default.
- W2061874270 hasConcept C164705383 @default.
- W2061874270 hasConcept C2779134260 @default.
- W2061874270 hasConcept C3018906752 @default.
- W2061874270 hasConcept C71924100 @default.
- W2061874270 hasConcept C95190672 @default.
- W2061874270 hasConceptScore W2061874270C11783203 @default.