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- W2061889586 abstract "Background/Aims: There is a general lack of cost-effectiveness evidence for positron emission tomography (PET) scan use in cancer suitable to support decision-making, and specifically for post-nonsurgical treatment of squamous cell carcinoma of the oropharynx (SCOOP). The value of effectiveness research is greatest when there are considerable data challenges and uncertainty due to early adoption of new technology and/or emerging serious high-growth disease. New expensive technology commonly becomes the standard of care without adequate evidence to support its value, including whether its performance does more good than harm to patients compared to the previous standard or alternatives. An example is the lack of evidence-informed standards for postchemoradiation imaging of SCOOP for patient management. The standard of care is posttreatment physical examination with imaging at 8–12 weeks using PET scan, computed tomography scan or ultrasound. Due to limits in the sensitivity and negative predictive value of these alternatives, patients may be over- or undertreated. A particular concern is PET scans are routinely used in practice although they have a high false-positive rate, which often result in unnecessary procedures." @default.
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- W2061889586 date "2015-04-30" @default.
- W2061889586 modified "2023-10-10" @default.
- W2061889586 title "Using Systematic Review and Decision Modeling to Fill Gaps in Evidence: Application to Positron Emission Tomography Scan Use in Posttreatment Squamous Cell Carcinoma of the Oropharynx" @default.
- W2061889586 doi "https://doi.org/10.17294/2330-0698.1167" @default.
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