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- W2061955385 abstract "Several genetic and epigenetic factors, both in the cell and in the host, contribute to the progression of tumors towards metastases. The escape of cancer cells from a primary, localized tumor to distant organs transforms a relatively curable pathology to an almost untreatable one. Metastatic lesions are often resistant to cancer therapy because of the progressive phenotypic changes that they have undergone. In this article we will give a <I>bird's eye</I> view on the features of metastatic cells and potential therapeutic targets. In particular, the invasion of basement membranes represents a fundamental step for cell dispersion. Over seventeen years ago we established the Matrigel" @default.
- W2061955385 created "2016-06-24" @default.
- W2061955385 creator A5031245175 @default.
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- W2061955385 creator A5051544577 @default.
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- W2061955385 date "2004-01-01" @default.
- W2061955385 modified "2023-09-29" @default.
- W2061955385 title "The chemoinvasion assay: a tool to study tumor and endothelial cell invasion of basement membranes" @default.
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- W2061955385 doi "https://doi.org/10.1387/ijdb.041822aa" @default.
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