Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062023900> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2062023900 endingPage "475" @default.
- W2062023900 startingPage "471" @default.
- W2062023900 abstract "The cytogenetic and clinical course of three patients allografted for Ph positive chronic myeloid leukaemia are reported. All patients had a peculiar pattern of relapse. Two out of three patients had donor marrow graft pretreated with monoclonal antibody for graft versus host prevention. The cytogenetic relapse was invariably associated with major morphological changes in the marrow indicating that these were also haematological relapses. However, no changes in the peripheral blood count were observed. When relapse occurred in these patients, Ph positive marrow metaphases and host red blood cells ranged from 75% to 100% of the total cell population: thereafter they spontaneously reverted to complete chimaerism. Therefore the presence of leukaemic cells even in considerable amount was not sufficient, per se, to prevail over normal marrow. In addition these observations indicate that relapse was not associated with elimination of the graft: while haemopoiesis was entirely of recipient origin the donor normal stem cells were present and vital although functionally silent. These data suggest that, although TBI remains the more effective tool for eradicating the majority of leukaemic cells, haemopoietic competition between host and donor marrow may have a major impact on leukaemic relapse." @default.
- W2062023900 created "2016-06-24" @default.
- W2062023900 creator A5007440569 @default.
- W2062023900 creator A5007754732 @default.
- W2062023900 creator A5017966262 @default.
- W2062023900 creator A5021642537 @default.
- W2062023900 creator A5027175065 @default.
- W2062023900 creator A5033482554 @default.
- W2062023900 creator A5065057353 @default.
- W2062023900 creator A5071392956 @default.
- W2062023900 creator A5082210832 @default.
- W2062023900 date "2008-07-07" @default.
- W2062023900 modified "2023-10-17" @default.
- W2062023900 title "Competition between recipient and donor cells after bone marrow transplantation for chronic myeloid leukaemia" @default.
- W2062023900 cites W1963662819 @default.
- W2062023900 cites W1977661390 @default.
- W2062023900 cites W2001348978 @default.
- W2062023900 cites W2002696114 @default.
- W2062023900 cites W2050642909 @default.
- W2062023900 cites W2065086752 @default.
- W2062023900 cites W2067480394 @default.
- W2062023900 cites W2068464067 @default.
- W2062023900 cites W2327418980 @default.
- W2062023900 cites W51426489 @default.
- W2062023900 cites W5387557 @default.
- W2062023900 cites W92426089 @default.
- W2062023900 doi "https://doi.org/10.1111/j.1365-2141.1988.00449.x-i1" @default.
- W2062023900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3044441" @default.
- W2062023900 hasPublicationYear "2008" @default.
- W2062023900 type Work @default.
- W2062023900 sameAs 2062023900 @default.
- W2062023900 citedByCount "17" @default.
- W2062023900 crossrefType "journal-article" @default.
- W2062023900 hasAuthorship W2062023900A5007440569 @default.
- W2062023900 hasAuthorship W2062023900A5007754732 @default.
- W2062023900 hasAuthorship W2062023900A5017966262 @default.
- W2062023900 hasAuthorship W2062023900A5021642537 @default.
- W2062023900 hasAuthorship W2062023900A5027175065 @default.
- W2062023900 hasAuthorship W2062023900A5033482554 @default.
- W2062023900 hasAuthorship W2062023900A5065057353 @default.
- W2062023900 hasAuthorship W2062023900A5071392956 @default.
- W2062023900 hasAuthorship W2062023900A5082210832 @default.
- W2062023900 hasConcept C109159458 @default.
- W2062023900 hasConcept C126322002 @default.
- W2062023900 hasConcept C203014093 @default.
- W2062023900 hasConcept C2779282312 @default.
- W2062023900 hasConcept C2780007613 @default.
- W2062023900 hasConcept C28328180 @default.
- W2062023900 hasConcept C2908647359 @default.
- W2062023900 hasConcept C2911091166 @default.
- W2062023900 hasConcept C54355233 @default.
- W2062023900 hasConcept C71924100 @default.
- W2062023900 hasConcept C86803240 @default.
- W2062023900 hasConcept C99454951 @default.
- W2062023900 hasConceptScore W2062023900C109159458 @default.
- W2062023900 hasConceptScore W2062023900C126322002 @default.
- W2062023900 hasConceptScore W2062023900C203014093 @default.
- W2062023900 hasConceptScore W2062023900C2779282312 @default.
- W2062023900 hasConceptScore W2062023900C2780007613 @default.
- W2062023900 hasConceptScore W2062023900C28328180 @default.
- W2062023900 hasConceptScore W2062023900C2908647359 @default.
- W2062023900 hasConceptScore W2062023900C2911091166 @default.
- W2062023900 hasConceptScore W2062023900C54355233 @default.
- W2062023900 hasConceptScore W2062023900C71924100 @default.
- W2062023900 hasConceptScore W2062023900C86803240 @default.
- W2062023900 hasConceptScore W2062023900C99454951 @default.
- W2062023900 hasIssue "4" @default.
- W2062023900 hasLocation W20620239001 @default.
- W2062023900 hasLocation W20620239002 @default.
- W2062023900 hasOpenAccess W2062023900 @default.
- W2062023900 hasPrimaryLocation W20620239001 @default.
- W2062023900 hasRelatedWork W1977841877 @default.
- W2062023900 hasRelatedWork W1978598034 @default.
- W2062023900 hasRelatedWork W1982854051 @default.
- W2062023900 hasRelatedWork W2000367099 @default.
- W2062023900 hasRelatedWork W2052062369 @default.
- W2062023900 hasRelatedWork W2076188533 @default.
- W2062023900 hasRelatedWork W2253242983 @default.
- W2062023900 hasRelatedWork W2412102303 @default.
- W2062023900 hasRelatedWork W2612954527 @default.
- W2062023900 hasRelatedWork W3135157890 @default.
- W2062023900 hasVolume "69" @default.
- W2062023900 isParatext "false" @default.
- W2062023900 isRetracted "false" @default.
- W2062023900 magId "2062023900" @default.
- W2062023900 workType "article" @default.