FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062082127> ?p ?o ?g. }

• W2062082127 endingPage "385" @default.
• W2062082127 startingPage "375" @default.
• W2062082127 abstract "This study investigated the herb-drug interaction of xanthorrhizol and tamoxifen in human breast cancer cells. Using MCF-7 cell line as an in vitro model, the herb-drug interaction between xanthorrhizol and tamoxifen was measured by MTT assay, luciferase reporter assay, and cell cycle analysis. The effects of xanthorrhizol on growth/autophagy related signaling were determined by immunostaining, western blotting, and real time RT-PCR. Additionally, the in vivo effect of xanthorrhizol and tamoxifen on athymic nude mice implanted with MCF-7 cells was evaluated. When MCF-7 cells were co-treated with tamoxifen and xanthorrhizol, there were no significant changes in terms of cell number, luciferase activity, percentage S-phase cells and LC3-II expression. However, using the MCF-7 implanted nude mice model, it was possible to detect significantly increased tumor volumes, a larger tumor size, and increased protein expression of P38 and P27(Kip1) in the xanthorrhizol + tamoxifen group compared to the tamoxifen-alone group. It can be concluded that while there is no significant herb-drug interaction between xanthorrhizol and tamoxifen in vitro, there is such an interaction in tumor-bearing mice, which provides important information that affects breast cancer treatment translational research." @default.
• W2062082127 created "2016-06-24" @default.
• W2062082127 creator A5002505947 @default.
• W2062082127 creator A5003537346 @default.
• W2062082127 creator A5016453981 @default.
• W2062082127 creator A5018076277 @default.
• W2062082127 creator A5044222415 @default.
• W2062082127 creator A5058153748 @default.
• W2062082127 creator A5072571883 @default.
• W2062082127 creator A5083141060 @default.
• W2062082127 creator A5084074772 @default.
• W2062082127 date "2014-01-01" @default.
• W2062082127 modified "2023-10-16" @default.
• W2062082127 title "In Vitro and In Vivo Effects of Xanthorrhizol on Human Breast Cancer MCF-7 Cells Treated With Tamoxifen" @default.
• W2062082127 cites W1902141597 @default.
• W2062082127 cites W1970747178 @default.
• W2062082127 cites W1980291874 @default.
• W2062082127 cites W2005040501 @default.
• W2062082127 cites W2007341982 @default.
• W2062082127 cites W2009439253 @default.
• W2062082127 cites W2011459509 @default.
• W2062082127 cites W2014432073 @default.
• W2062082127 cites W2022624995 @default.
• W2062082127 cites W2051294986 @default.
• W2062082127 cites W2053357590 @default.
• W2062082127 cites W2055959517 @default.
• W2062082127 cites W2083576875 @default.
• W2062082127 cites W2088714851 @default.
• W2062082127 cites W2125557137 @default.
• W2062082127 cites W2144257911 @default.
• W2062082127 cites W2145265436 @default.
• W2062082127 cites W2147443535 @default.
• W2062082127 cites W2155454155 @default.
• W2062082127 cites W2917423152 @default.
• W2062082127 cites W4249000216 @default.
• W2062082127 cites W4293247451 @default.
• W2062082127 cites W91452638 @default.
• W2062082127 doi "https://doi.org/10.1254/jphs.14024fp" @default.
• W2062082127 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25141924" @default.
• W2062082127 hasPublicationYear "2014" @default.
• W2062082127 type Work @default.
• W2062082127 sameAs 2062082127 @default.
• W2062082127 citedByCount "13" @default.
• W2062082127 countsByYear W20620821272015 @default.
• W2062082127 countsByYear W20620821272016 @default.
• W2062082127 countsByYear W20620821272017 @default.
• W2062082127 countsByYear W20620821272019 @default.
• W2062082127 countsByYear W20620821272020 @default.
• W2062082127 countsByYear W20620821272022 @default.
• W2062082127 countsByYear W20620821272023 @default.
• W2062082127 crossrefType "journal-article" @default.
• W2062082127 hasAuthorship W2062082127A5002505947 @default.
• W2062082127 hasAuthorship W2062082127A5003537346 @default.
• W2062082127 hasAuthorship W2062082127A5016453981 @default.
• W2062082127 hasAuthorship W2062082127A5018076277 @default.
• W2062082127 hasAuthorship W2062082127A5044222415 @default.
• W2062082127 hasAuthorship W2062082127A5058153748 @default.
• W2062082127 hasAuthorship W2062082127A5072571883 @default.
• W2062082127 hasAuthorship W2062082127A5083141060 @default.
• W2062082127 hasAuthorship W2062082127A5084074772 @default.
• W2062082127 hasBestOaLocation W20620821271 @default.
• W2062082127 hasConcept C109541995 @default.
• W2062082127 hasConcept C121608353 @default.
• W2062082127 hasConcept C126322002 @default.
• W2062082127 hasConcept C150903083 @default.
• W2062082127 hasConcept C185592680 @default.
• W2062082127 hasConcept C202751555 @default.
• W2062082127 hasConcept C207001950 @default.
• W2062082127 hasConcept C2777176818 @default.
• W2062082127 hasConcept C2780783641 @default.
• W2062082127 hasConcept C2994423619 @default.
• W2062082127 hasConcept C502942594 @default.
• W2062082127 hasConcept C530470458 @default.
• W2062082127 hasConcept C55493867 @default.
• W2062082127 hasConcept C71924100 @default.
• W2062082127 hasConcept C86803240 @default.
• W2062082127 hasConcept C98274493 @default.
• W2062082127 hasConceptScore W2062082127C109541995 @default.
• W2062082127 hasConceptScore W2062082127C121608353 @default.
• W2062082127 hasConceptScore W2062082127C126322002 @default.
• W2062082127 hasConceptScore W2062082127C150903083 @default.
• W2062082127 hasConceptScore W2062082127C185592680 @default.
• W2062082127 hasConceptScore W2062082127C202751555 @default.
• W2062082127 hasConceptScore W2062082127C207001950 @default.
• W2062082127 hasConceptScore W2062082127C2777176818 @default.
• W2062082127 hasConceptScore W2062082127C2780783641 @default.
• W2062082127 hasConceptScore W2062082127C2994423619 @default.
• W2062082127 hasConceptScore W2062082127C502942594 @default.
• W2062082127 hasConceptScore W2062082127C530470458 @default.
• W2062082127 hasConceptScore W2062082127C55493867 @default.
• W2062082127 hasConceptScore W2062082127C71924100 @default.
• W2062082127 hasConceptScore W2062082127C86803240 @default.
• W2062082127 hasConceptScore W2062082127C98274493 @default.
• W2062082127 hasIssue "4" @default.
• W2062082127 hasLocation W20620821271 @default.
• W2062082127 hasLocation W20620821272 @default.
• W2062082127 hasLocation W20620821273 @default.
• W2062082127 hasOpenAccess W2062082127 @default.

• next