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- W2062091289 abstract "Acute kidney injury (AKI) is a frequent complication in the intensive care unit with limited therapeutic modalities. Although survival from isolated AKI has improved with recent advancements in renal replacement therapy, mortality from AKI complicated by multiorgan dysfunction has remained unchanged and is estimated to be approximately 50%. Hence, defining and better understanding the pathophysiology of distant organ dysfunction associated with AKI is clinically important because it may lead to new treatment strategies. In animal models, it has become increasingly clear that AKI is not an isolated event but results in remote organ dysfunction involving the heart, lungs, liver, intestines, and brain through an inflammatory mechanism that involves neutrophil migration, cytokine expression, and increased oxidative stress. The purpose of this brief review is to summarize the human and basic science evidence for AKI and its detrimental effects on distant organs." @default.
- W2062091289 created "2016-06-24" @default.
- W2062091289 creator A5027851201 @default.
- W2062091289 creator A5054941006 @default.
- W2062091289 date "2012-05-01" @default.
- W2062091289 modified "2023-10-01" @default.
- W2062091289 title "Acute Kidney Injury and Extrarenal Organ Dysfunction" @default.
- W2062091289 cites W1544769291 @default.
- W2062091289 cites W181593226 @default.
- W2062091289 cites W1855316965 @default.
- W2062091289 cites W1948268265 @default.
- W2062091289 cites W1965282985 @default.
- W2062091289 cites W1967270772 @default.
- W2062091289 cites W1967300023 @default.
- W2062091289 cites W1972983715 @default.
- W2062091289 cites W1974159422 @default.
- W2062091289 cites W1974400821 @default.
- W2062091289 cites W1981554819 @default.
- W2062091289 cites W1985491668 @default.
- W2062091289 cites W1986898371 @default.
- W2062091289 cites W1987293815 @default.
- W2062091289 cites W1988629947 @default.
- W2062091289 cites W1990632655 @default.
- W2062091289 cites W1990675823 @default.
- W2062091289 cites W1990892782 @default.
- W2062091289 cites W1991838261 @default.
- W2062091289 cites W1996271604 @default.
- W2062091289 cites W1998226806 @default.
- W2062091289 cites W2007410147 @default.
- W2062091289 cites W2008785905 @default.
- W2062091289 cites W2012466772 @default.
- W2062091289 cites W2015960698 @default.
- W2062091289 cites W2016780014 @default.
- W2062091289 cites W2017494661 @default.
- W2062091289 cites W2022473516 @default.
- W2062091289 cites W2029723446 @default.
- W2062091289 cites W2032049260 @default.
- W2062091289 cites W2033242537 @default.
- W2062091289 cites W2043132544 @default.
- W2062091289 cites W2047830531 @default.
- W2062091289 cites W2049553703 @default.
- W2062091289 cites W2049653407 @default.
- W2062091289 cites W2051338691 @default.
- W2062091289 cites W2056449665 @default.
- W2062091289 cites W2058454285 @default.
- W2062091289 cites W2059804741 @default.
- W2062091289 cites W2060017302 @default.
- W2062091289 cites W2063254774 @default.
- W2062091289 cites W2066885413 @default.
- W2062091289 cites W2067117096 @default.
- W2062091289 cites W2068018103 @default.
- W2062091289 cites W2074801801 @default.
- W2062091289 cites W2076874068 @default.
- W2062091289 cites W2077944368 @default.
- W2062091289 cites W2080935560 @default.
- W2062091289 cites W2085039333 @default.
- W2062091289 cites W2093360836 @default.
- W2062091289 cites W2094729588 @default.
- W2062091289 cites W2094758488 @default.
- W2062091289 cites W2094802457 @default.
- W2062091289 cites W2098722533 @default.
- W2062091289 cites W2101754323 @default.
- W2062091289 cites W2103829016 @default.
- W2062091289 cites W2109348687 @default.
- W2062091289 cites W2117958746 @default.
- W2062091289 cites W2127911797 @default.
- W2062091289 cites W2128663650 @default.
- W2062091289 cites W2128734884 @default.
- W2062091289 cites W2133482423 @default.
- W2062091289 cites W2135154890 @default.
- W2062091289 cites W2138877453 @default.
- W2062091289 cites W2139791477 @default.
- W2062091289 cites W2139937737 @default.
- W2062091289 cites W2144000554 @default.
- W2062091289 cites W2146350062 @default.
- W2062091289 cites W2150737557 @default.
- W2062091289 cites W2157493207 @default.
- W2062091289 cites W2161481747 @default.
- W2062091289 cites W2161533677 @default.
- W2062091289 cites W2171344771 @default.
- W2062091289 cites W2171423579 @default.
- W2062091289 cites W2272705881 @default.
- W2062091289 cites W2315072496 @default.
- W2062091289 cites W2324476825 @default.
- W2062091289 cites W2601638366 @default.
- W2062091289 cites W39676344 @default.
- W2062091289 cites W408225 @default.
- W2062091289 cites W55388696 @default.
- W2062091289 cites W87960664 @default.
- W2062091289 doi "https://doi.org/10.1097/aln.0b013e31824f951b" @default.
- W2062091289 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22415388" @default.
- W2062091289 hasPublicationYear "2012" @default.
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