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- W2062103540 abstract "SUMMARY This review updates the mechanism of action of levonorgestrel (LNG) used for emergency contraception. A critical analysis of estimates of the contraceptive efficacy of LNG indicates that its failure rate is higher than previously reported. Under the effect of LNG, cervical mucus turns highly viscous and hinders the exit of sperm from the cervical reservoir needed to renew the sperm population at the site of fertilization. Several authors have documented that LNG suppresses the preovulatory surge of gonadotropins and interferes with the ovulatory process in women and in animal models. LNG does not interfere with embryo implantation in rats and Cebus apella, when it is administered after fertilization. In conclusion, LNG prevents pregnancy only when it is administered at a time of the menstrual cycle in which it can impede fertilization and the method fails when it is given at later stages of the cycle." @default.
- W2062103540 created "2016-06-24" @default.
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- W2062103540 date "2004-01-01" @default.
- W2062103540 modified "2023-09-30" @default.
- W2062103540 title "MECANISMO DE ACCIÓN DEL LEVONORGESTREL EN LA ANTICONCEPCIÓN DE EMERGENCIA" @default.
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- W2062103540 doi "https://doi.org/10.4067/s0717-75262004000200011" @default.
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